Absence of E17K mutation in the pleckstrin homology domain of AKT1 in gastrointestinal and liver cancers in the Korean population

被引：2

作者：

Cao, Zhang ^{[1
]}

Song, Jae Hwi ^{[1
]}

Kim, Chang Jae ^{[1
]}

Cho, Yong Gu ^{[1
]}

Kim, Su Young ^{[1
]}

Nam, Suk Woo ^{[1
]}

Lee, Jung Young ^{[1
]}

Park, Won Sang ^{[1
]}

机构：

[1] Catholic Univ, Dept Pathol, Coll Med, Seoul 137701, South Korea

来源：

APMIS | 2008年 / 116卷 / 06期

关键词：

D O I：

10.1111/j.1600-0463.2008.00998.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：530 / 533

页数：4

共 31 条

[21] cAMP stimulates protein kinase B in a Wortmannin-insensitive manner [J].

Sable, CL ;

Filippa, N ;

Hemmings, B ;

VanObberghen, E .

FEBS LETTERS, 1997, 409 (02) :253-257

[22] PIK3CA is implicated as an oncogene in ovarian cancer [J].

Shayesteh, L ;

Lu, YL ;

Kuo, WL ;

Baldocchi, R ;

Godfrey, T ;

Collins, C ;

Pinkel, D ;

Powell, B ;

Mills, GB ;

Gray, JW .

NATURE GENETICS, 1999, 21 (01) :99-102

[23] The consensus coding sequences of human breast and colorectal cancers [J].

Sjoeblom, Tobias ;

Jones, Sian ;

Wood, Laura D. ;

Parsons, D. Williams ;

Lin, Jimmy ;

Barber, Thomas D. ;

Mandelker, Diana ;

Leary, Rebecca J. ;

Ptak, Janine ;

Silliman, Natalie ;

Szabo, Steve ;

Buckhaults, Phillip ;

Farrell, Christopher ;

Meeh, Paul ;

Markowitz, Sanford D. ;

Willis, Joseph ;

Dawson, Dawn ;

Willson, James K. V. ;

Gazdar, Adi F. ;

Hartigan, James ;

Wu, Leo ;

Liu, Changsheng ;

Parmigiani, Giovanni ;

Park, Ben Ho ;

Bachman, Kurtis E. ;

Papadopoulos, Nickolas ;

Vogelstein, Bert ;

Kinzler, Kenneth W. ;

Velculescu, Victor E. .

SCIENCE, 2006, 314 (5797) :268-274

[24] The activation of Akt/PKB signaling pathway and cell survival [J].

Song, G ;

Ouyang, GL ;

Bao, SD .

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2005, 9 (01) :59-71

[25] Essential role of AKT-1/protein kinase Bα in PTEN-controlled tumorigenesis [J].

Stiles, B ;

Gilman, V ;

Khanzenzon, N ;

Lesche, R ;

Li, A ;

Qiao, R ;

Liu, X ;

Wu, H .

MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (11) :3842-3851

[26] AKT1/PKBα kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells [J].

Sun, M ;

Wang, G ;

Paciga, JE ;

Feldman, RI ;

Yuan, ZQ ;

Ma, XL ;

Shelley, SA ;

Jove, R ;

Tsichlis, PN ;

Nicosia, SV ;

Cheng, JQ .

AMERICAN JOURNAL OF PATHOLOGY, 2001, 159 (02) :431-437

[27] Commentary - AKT plays a central role in tumorigenesis [J].

Testa, JR ;

Bellacosa, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (20) :10983-10985

[28] The PI3K-PDK1 connection: more than just a road to PKB [J].

Vanhaesebroeck, B ;

Alessi, DR .

BIOCHEMICAL JOURNAL, 2000, 346 (pt 3) :561-576

[29] The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling [J].

Vazquez, F ;

Sellers, WR .

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2000, 1470 (01) :M21-M35

[30] The phosphatidylinositol 3-kinase-AKT pathway in human cancer [J].

Vivanco, I ;

Sawyers, CL .

NATURE REVIEWS CANCER, 2002, 2 (07) :489-501

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