Numerical simulation of lateral migration of red blood cells in Poiseuille flows

被引：25
作者：
Shi, Lingling [1 ]
Pan, Tsorng-Whay [1 ]
Glowinski, Roland [1 ]
机构：
[1] Univ Houston, Dept Math, Houston, TX 77204 USA
来源：
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS | 2012年 / 68卷 / 11期
基金：
美国国家科学基金会;
关键词：
red blood cells; lateral migration; elastic spring model; immersed boundary method; micro-channel; Poiseuille flow; LATTICE-BOLTZMANN; MOTION; MODEL; PARTICLE; DEFORMATION; MEMBRANE; DYNAMICS; VESICLE;
D O I：
10.1002/fld.2455
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
A spring model is applied to simulate the skeleton structure of the red blood cell (RBC) membrane and to study the RBC rheology in two-dimensional Poiseuille flows using an immersed boundary method. The lateral migration properties of the cells in Poiseuille flows have been investigated. The simulation results show that the rate of migration toward the center of the channel depends on the swelling ratio and the deformability of the cells. We have also combined the above methodology with a fictitious domain method to study the motion of RBCs in a two-dimensional micro-channel with a constriction with an application to blood plasma separation. Copyright (C) 2010 John Wiley & Sons, Ltd.
引用
收藏
页码：1393 / 1408
页数：16
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