Activities of therapeutic agents and myristamidopropyl dimethylamine against Acanthamoeba isolates

被引:38
作者
Kilvington, S
Hughes, R
Byas, J
Dart, J
机构
[1] Univ Leicester, Dept Microbiol & Immunol, Leicester LE1 9HN, Leics, England
[2] Moorfields Eye Hosp, Dept Ophthalmol, London EC1V 2PD, England
关键词
D O I
10.1128/AAC.46.6.2007-2009.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The activities of therapeutic agents and myristamidopropyl dimethylamine (MAPD) against Acanthamoeba strains recalcitrant to medical therapy were studied. MAPD minimum cysticidal concentrations were 6.25 to 25 mug/ml; 10 to 30 mug/ml gave at least a 3-log cyst kill after 6 h, and 50 and 100 mug/ml gave at least a 3-log cyst kill within 2 and 1 h, respectively.
引用
收藏
页码:2007 / 2009
页数:3
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