THERAPEUTIC MANAGEMENT OF AN IGA NEPHROPATHY CASE AND DISEASE REVIEW

被引:0
|
作者
Lococo, Bruno [1 ]
Alberton, Valeria [2 ]
Fazzini, Bernarda [1 ]
Smuclir Quevedo, Alejandra [1 ]
Mo-Rales, Diego [1 ]
Malvar, Ana [1 ]
机构
[1] Hosp Gen Agudos Dr Juan A Fernandez, Serv Nefrol, Buenos Aires, DF, Argentina
[2] Hosp Gen Agudos Dr Juan A Fernandez, Serv Anat Patol, Buenos Aires, DF, Argentina
来源
REVISTA DE NEFROLOGIA DIALISIS Y TRASPLANTE | 2016年 / 36卷 / 02期
关键词
immunoglobulin A nephropathy; IgA; Berger disease; pathogeny; theraphy; RANDOMIZED CONTROLLED-TRIAL; ISOLATED MICROSCOPIC HEMATURIA; IMMUNOGLOBULIN-A NEPHROPATHY; TERM CONTROLLED TRIAL; OXFORD CLASSIFICATION; MYCOPHENOLATE-MOFETIL; O-GLYCOSYLATION; FOLLOW-UP; KIDNEY-TRANSPLANTATION; RENAL-TRANSPLANTATION;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Inmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical presentation is extremely variable and can vary from isolated microhematuria up to a severe damage of renal function due to superimposed extracapillary glomerulonephritis. Initially it was considered an entity with good prognosis, but over time and more knowledge about IgAN, it was shown that 20 to 30% of 20 years old patients evolved to end stage renal failure and other 20% had important renal function loss. In the present article we describe a case of a patient in whom we detected by chance renal damage markers in the urine, and then the histologic findings observed in renal biopsy, modified the prognosis and therapeutic procedure. From this clinical case, we performed an update on IgA Nephropathy.
引用
收藏
页码:108 / 123
页数:16
相关论文
共 50 条
  • [21] Treatment of IgA Nephropathy: An Update
    Rosselli, Jennifer L.
    Thacker, Stacey M.
    Karpinski, Julie P.
    Petkewicz, Katherine A.
    ANNALS OF PHARMACOTHERAPY, 2011, 45 (10) : 1284 - 1296
  • [22] Mortality in Patients With IgA Nephropathy
    Knoop, Thomas
    Vikse, Bjorn Egil
    Svarstad, Einar
    Leh, Sabine
    Reisaeter, Anna Varberg
    Bjorneklett, Rune
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2013, 62 (05) : 883 - 890
  • [23] New therapeutic perspectives for IgA nephropathy in children
    Cambier, Alexandra
    Gleeson, Patrick J.
    Flament, Heloise
    Le Stang, Marie-Benedicte
    Monteiro, Renato C.
    PEDIATRIC NEPHROLOGY, 2021, 36 (03) : 497 - 506
  • [24] Uncoupling of Glomerular IgA Deposition and Disease Progression in Alymphoplasia Mice with IgA Nephropathy
    Aizawa, Masashi
    Suzuki, Yusuke
    Suzuki, Hitoshi
    Pang, Huihua
    Kihara, Masao
    Nakata, Junichiro
    Yamaji, Kenji
    Horikoshi, Satoshi
    Tomino, Yasuhiko
    PLOS ONE, 2014, 9 (04):
  • [25] Polycythemia vera associated with IgA nephropathy: A case report and literature review
    Chen, Hong
    Zhang, Baohe
    Li, Mingxu
    Hu, Ruilan
    Zhou, Chunhua
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2015, 10 (02) : 555 - 560
  • [26] A Child With Concomitant Neuroblastoma and IgA Nephropathy: A Case Report and Literature Review
    Yu, Ling
    Wang, Jingjing
    Feng, Chunyue
    Huang, Guoping
    Gu, Weizhong
    Xiong, Jieni
    Mao, Jianhua
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (05)
  • [27] Novel therapy for anti-glomerular basement membrane disease with IgA nephropathy: A case report
    Xu, Dechao
    Wu, Jianxiang
    Wu, Jun
    Xu, Chenggang
    Zhang, Yuqiang
    Mei, Changlin
    Gao, Xiang
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2016, 11 (05) : 1889 - 1892
  • [28] Immunosuppressive agents for treating IgA nephropathy
    Vecchio, Mariacristina
    Bonerba, Bibiana
    Palmer, Suetonia C.
    Craig, Jonathan C.
    Ruospo, Marinella
    Samuels, Joshua A.
    Molony, Donald A.
    Schena, Francesco Paolo
    Strippoli, Giovanni F. M.
    COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2015, (08):
  • [29] Behcet's disease and IgA nephropathy
    Altay, Mustafa
    Secilmis, Sema
    Unverdi, Selman
    Ceri, Mevlut
    Duranay, Murat
    RHEUMATOLOGY INTERNATIONAL, 2012, 32 (07) : 2227 - 2229
  • [30] Drugs in Development to Treat IgA Nephropathy
    Del Vecchio, Lucia
    Allinovi, Marco
    Comolli, Stefania
    Peiti, Silvia
    Rimoldi, Chiara
    Locatelli, Francesco
    DRUGS, 2024, 84 (05) : 503 - 525