Obesity as a risk factor in COVID-19: Possible mechanisms and implications

被引：35

作者：

Petrova, Dafina ^{[1
,2
,3
]}

Salamanca-Fernandez, Elena ^{[1
,2
,3
]}

Rodriguez Barranco, Miguel ^{[1
,2
,3
]}

Navarro Perez, Pilar ^{[1
]}

Jimenez Moleon, Jose Juan ^{[2
,3
,4
]}

Sanchez, Maria-Jose ^{[1
,2
,3
,4
]}

机构：

[1] Escuela Andaluza Salud Publ EASP, Granada, Spain

[2] Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain

[3] Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Madrid, Spain

[4] Univ Granada, Dept Med Prevent & Salud Publ, Granada, Spain

来源：

ATENCION PRIMARIA | 2020年 / 52卷 / 07期

关键词：

COVID-19; SARS-CoV-2; Pandemic; Obesity; Overweight;

D O I：

10.1016/j.aprim.2020.05.003

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Recent reports suggest that obesity is a risk factor for more severe coronavirus disease. This article summarizes the available scientific evidence on the rote of obesity in COVID-19. We focus on implications for younger patients and the proposed biological mechanisms that could explain both the higher risk observed and the possible higher contagiousness of people with obesity. We consider implications of the pandemic for people with obesity in relation to: difficulties in managing hospitalized patients, implications of confinement for the control and treatment of obesity, and the stigma people with obesity suffer, that could increase should the relationship between obesity and COVID-19 be confirmed. Understanding the role of obesity in COVID-19 should be a public health priority, given the high prevalence of this condition in our country. (C) 2020 The Authors. Published by Elsevier Espana, S.L.U.

引用

页码：496 / 500

页数：5

共 28 条

[21] Joint international consensus statement for ending stigma of obesity [J].

Rubino, Francesco ;

Puhl, Rebecca M. ;

Cummings, David E. ;

Eckel, Robert H. ;

Ryan, Donna H. ;

Mechanick, Jeffrey I. ;

Nadglowski, Joe ;

Ramos Salas, Ximena ;

Schauer, Phillip R. ;

Twenefour, Douglas ;

Apovian, Caroline M. ;

Aronne, Louis J. ;

Batterham, Rachel L. ;

Berthoud, Hans-Rudolph ;

Boza, Camilo ;

Busetto, Luca ;

Dicker, Dror ;

De Groot, Mary ;

Eisenberg, Daniel ;

Flint, Stuart W. ;

Huang, Terry T. ;

Kaplan, Lee M. ;

Kirwan, John P. ;

Korner, Judith ;

Kyle, Ted K. ;

Laferrere, Blandine ;

le Roux, Carel W. ;

McIver, LaShawn ;

Mingrone, Geltrude ;

Nece, Patricia ;

Reid, Tirissa J. ;

Rogers, Ann M. ;

Rosenbaum, Michael ;

Seeley, Randy J. ;

Torres, Antonio J. ;

Dixon, John B. .

NATURE MEDICINE, 2020, :485-497

[22]

Sattar N, 2020, CIRCULATION, DOI [10.1016/j.metabot.2020.154251, DOI 10.1016/J.METAB0T.2020.154251]

[23] High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation [J].

Simonnet, Arthur ;

Chetboun, Mikael ;

Poissy, Julien ;

Raverdy, Violeta ;

Noulette, Jerome ;

Duhamel, Alain ;

Labreuche, Julien ;

Mathieu, Daniel ;

Pattou, Francois ;

Jourdain, Merce .

OBESITY, 2020, 28 (07) :1195-1199

[24]

Sociedad Espanola de Obesidad (SEEDO), 2020, REC RUT SAL CONF

[25] Obesity and impaired metabolic health in patients with COVID-19 [J].

Stefan, Norbert ;

Birkenfeld, Andreas L. ;

Schulze, Matthias B. ;

Ludwig, David S. .

NATURE REVIEWS ENDOCRINOLOGY, 2020, 16 (07) :341-342

[26] Obesity as a Disease [J].

Upadhyay, Jagriti ;

Farr, Olivia ;

Perakakis, Nikolaos ;

Ghaly, Wael ;

Mantzoros, Christos .

MEDICAL CLINICS OF NORTH AMERICA, 2018, 102 (01) :13-33

[27]

World Obesity Federation, 2020, COR COVID 19 OB

[28]

Zomeno MD., 2019, Rev Esp Cardiol, V72, P916, DOI [10.1016/j.recesp.2018.07.009, DOI 10.1016/J.RECESP.2018.07.009]

← 1 2 3 →