Characterization of a novel series of potent, selective inhibitors of wild type and mutant/fusion anaplastic lymphoma kinase

被引：6

作者：

Wilcoxen, Keith M. ^{[1
]}

Brake, Rachael L. ^{[2
]}

Saffran, Doug ^{[2
]}

Teffera, Yohannes ^{[2
]}

Choguette, Deborah ^{[2
]}

Whittington, Doug ^{[2
]}

Yu, Violeta ^{[2
]}

Romero, Karina ^{[2
]}

Bode, Christiane ^{[2
]}

Stellwagen, John ^{[2
]}

Potashman, Michelle ^{[2
]}

Emkey, Renee ^{[2
]}

Andrews, Paul ^{[2
]}

Drew, Allison E. ^{[2
]}

Xu, Man ^{[2
]}

Szilvassy, Stephen ^{[3
]}

Al-Assad, Samer ^{[3
]}

Lewis, Richard T. ^{[2
]}

机构：

[1] Tesaro Inc, Waltham, MA USA

[2] Amgen Inc, Cambridge, MA USA

[3] Amgen Inc, Thousand Oaks, CA USA

来源：

CANCER RESEARCH | 2012年 / 72卷

关键词：

D O I：

10.1158/1538-7445.AM2012-1795

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1795

引用

页数：2

共 50 条

[31] Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors
Raeppel, Stephane L.
Gaudette, Frederic
Nguyen, Hannah
Beaulieu, Normand
Wang, James
Maroun, Christiane
Besterman, Jeffrey M.
Vaisburg, Arkadii
INTERNATIONAL JOURNAL OF MEDICINAL CHEMISTRY, 2012, 2012
[32] Identification of a novel series of potent RON receptor tyrosine kinase inhibitors
Raeppel, Stephane
Gaudette, Frederic
Mannion, Michael
Claridge, Stephen
Saavedra, Oscar
Isakovic, Ljubomir
Deziel, Robert
Beaulieu, Normand
Beaulieu, Carole
Dupont, Isabelle
Nguyen, Hannah
Wang, James
Macleod, A. Robert
Maroun, Christiane
Besterman, Jeffrey M.
Vaisburg, Arkadii
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (09) : 2745 - 2749
[33] Identification of a novel LRRC4C-ALK fusion in lung adenocarcinoma and outcome of the response to anaplastic lymphoma kinase inhibitors
Wang, Hongbiao
Li, ZhiFeng
Qi, Xiaofang
Wang, Wenjing
Lin, Yingcheng
JOURNAL OF GENE MEDICINE, 2021, 23 (03):
[34] Discovery and optimization of a novel series of potent inhibitors of mutant (V600E) B-Raf kinase
Vasbinder, Melissa
Aquila, Brian
Cook, Donald
Drew, Lisa
Fauber, Benjamin
Grondine, Michael
Hennessy, Edward
Lyne, Paul
Omer, Charles
Palakurthi, Sangeetha
Sha, Li
Shen, Minhui
Wang, Haixia
Ye, Minwei
CANCER RESEARCH, 2009, 69
[35] Synthesis, characterization of benzimidazole carboxamide derivatives as potent anaplastic lymphoma kinase inhibitor and antioxidant activity
Prabu, D. Sam Daniel
Lakshmanan, Sivalingam
Ramalakshmi, N.
Thirumurugan, K.
Govindaraj, Dharman
Antony, S. Arul
SYNTHETIC COMMUNICATIONS, 2019, 49 (02) : 266 - 278
[36] Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors
Jung, FH
Pasquet, G
Lambert-van der Brempt, C
Lohmann, JJM
Warin, N
Renaud, F
Germain, H
De Savi, C
Roberts, N
Johnson, T
Dousson, C
Hill, GB
Mortlock, AA
Heron, N
Wilkinson, RW
Wedge, SR
Heaton, SP
Odedra, R
Keen, NJ
Green, S
Brown, E
Thompson, K
Brightwell, S
JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (03) : 955 - 970
[37] Novel potent and selective inhibitors of protein kinase CK2
Prudent, R.
Moucadel, V
Laudet, B.
Cochet, C.
BULLETIN DU CANCER, 2008, 95 : S66 - S66
[38] Kinase-targeted libraries: The design and synthesis of novel, potent, and selective kinase inhibitors
Akritopoulou-Zanze, Irini
Hajduk, Philip J.
DRUG DISCOVERY TODAY, 2009, 14 (5-6) : 291 - 297
[39] Development of Alectinib-Based PROTACs as Novel Potent Degraders of Anaplastic Lymphoma Kinase (ALK)
Xie, Shaowen
Sun, Yuan
Liu, Yulin
Li, Xinnan
Li, Xinuo
Zhong, Wenyi
Zhan, Feiyan
Zhu, Jingjie
Yao, Hong
Yang, Dong-Hua
Chen, Zhe-Sheng
Xu, Jinyi
Xu, Shengtao
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (13) : 9120 - 9140
[40] Identifying Novel Mechanisms of Resistance to Tyrosine Kinase Inhibitors in Anaplastic Large Cell Lymphoma
Atabay, Elif
Wang, Qi
Chiara, Ambrogio
Cheong, Taek-Chin
Peola, Silvia
Sharma, Geeta G.
Mologni, Luca
Gambacorti-Passerini, Carlo
Voena, Claudia
Chiarle, Roberto
BLOOD, 2019, 134

← 1 2 3 4 5 →