Oligomeric acylphloroglucinols from myrtle (Myrtus communis)

被引：84
|
作者：
Appendino, G
Bianchi, F
Minassi, A
Sterner, O
Ballero, M
Gibbons, S
机构：
[1] Univ Piemonte Orientale, DISCAFF, I-28100 Novara, Italy
[2] Lund Univ, Dept Organ & Bioorgan Chem, S-22100 Lund, Sweden
[3] Univ Cagliari, Dipartimento Sci Bot, I-09123 Cagliari, Italy
[4] Univ London, Sch Pharm, Ctr Pharmacognosy & Phytotherapy, London WC1N 1AX, England
来源：
JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 03期
关键词：
D O I：
10.1021/np010441b
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.
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页码：334 / 338
页数：5
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