Applying mechanistic pharmacokinetic-pharmacodynamic models (PKPD) to describe the growth and inhibition of xenograft tumors in rats and mice by targeted anticancer agents

被引：0
|
作者：
Jones, Rhys D. O. [1 ]
de Almeida, Camila [1 ]
Dimelow, Richard [1 ]
Gibbons, Frank [2 ]
Schroeder, Patricia [2 ]
Walker, Mike [1 ]
Wilson, Joanne [1 ]
Yates, James W. T. [1 ]
Evans, Neil D. [3 ]
机构：
[1] AstraZeneca, Macclesfield, Cheshire, England
[2] AstraZeneca, Waltham, MA USA
[3] Univ Warwick, Sch Engn, Warwick, England
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-3777
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3777
引用
收藏
页数：1
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