Cherubism: clinicopathologic features

被引：36
作者：
Yamaguchi, T
Dorfman, HD
Eisig, S
机构：
[1] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Orthopaed Surg, Sect Orthopaed Pathol, Bronx, NY 10467 USA
[2] Dokkyo Univ, Sch Med, Dept Pathol, Mibu, Tochigi 3210293, Japan
[3] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Oral Surg, Bronx, NY 10467 USA
来源：
SKELETAL RADIOLOGY | 1999年 / 28卷 / 06期
关键词：
cherubism; familial multilocular cystic disease of the jaws giant-cell reparative granuloma; fibrous dysplasia;
D O I：
10.1007/s002560050530
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
A case of cherubism in 6-year-old boy is reported. He presented with bilateral symmetrical enlargement of the jaw in addition to medially dislocated premature teeth, narrow V-shaped palatal vault, and mild upward turning of the eyes. Radiographs showed multiloculated osteolysis in both the mandible and maxilla. Histology revealed a non-neoplastic fibrous lesion, rich in multinucleated giant cells, consistent with giant-cell reparative granuloma. Since the original description of cherubism, various histologic interpretations have been proposed, particularly that of fibrous dysplasia. However, it should be emphasized that cherubism is a disease histologically indistinguishable from giant-cell reparative granuloma.
引用
收藏
页码：350 / 353
页数：4
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