Synthesis of cinacalcet hydrochloride under solvent-free conditions

被引：0
|
作者：
Chavakula, Ramadas [1 ]
Mutyala, Narayana Rao [1 ]
Chennupati, Srinivasa Rao [1 ]
机构：
[1] Tyche Ind Ltd, Hyderabad 500093, Andhra Pradesh, India
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2013年 / 90卷 / 12期
关键词：
Calcimimetics; cinacalcet; reductive amination; solvent-free reaction; sodium borohydride; boric acid;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and convenient procedure for synthesis of cinacalcet hydrochloride by reductive amination of (R)-(1-naphthyl)ethylamine and 3[3-(trifluoromethyl)phenyl]propionaldehyde using sodium borohydride activated by boric acid, p-toluenesulfonic acid monohydrate or benzoic acid as reducing agent under solvent-free conditions is described.
引用
收藏
页码：2291 / 2292
页数：2
相关论文
共 50 条
  • [41] α-cyclisation of tertiary amines:: Synthesis of some novel annelated quinolines via a three-component reaction under solvent-free conditions
    Devi, Lpsita
    Baruah, BiswaJita
    Bhuyan, Pulak J.
    SYNLETT, 2006, (16) : 2593 - 2596
  • [42] Rapid, efficient and eco-friendly procedure for the synthesis of quinoxalines under solvent-free conditions using sulfated polyborate as a recyclable catalyst
    Indalkar, Krishna S.
    Khatri, Chetan K.
    Chaturbhuj, Ganesh U.
    JOURNAL OF CHEMICAL SCIENCES, 2017, 129 (02) : 141 - 148
  • [43] TMSCl-catalysed condensation of α-diketone compounds with urea/thiourea derivatives under solvent-free conditions
    Mobinikhaledi, Akbar
    Amiri, Alireza Khajeh
    JOURNAL OF CHEMICAL SCIENCES, 2013, 125 (05) : 1055 - 1062
  • [44] Ru(II)-NHC catalysed N-Alkylation of amines with alcohols under solvent-free conditions
    Karaca, Emine Ozge
    Dehimat, Zieneb Imene
    Yasar, Sedat
    Gurbuz, Nevin
    Tebbani, Dahmane
    Cetinkaya, Bekir
    Ozdemir, Ismail
    INORGANICA CHIMICA ACTA, 2021, 520
  • [45] Pd-catalyzed Dehalogenation of Aromatic Halides Under Solvent-free Conditions Using Hydrogen Balloon
    Chang, Fei
    Kim, Hakwon
    Lee, Byeongno
    Park, Hoon Gyu
    Park, Jaiwook
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2011, 32 (03): : 1074 - 1076
  • [46] An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions
    Xin Ying Zhang
    ChineseChemicalLetters, 2010, 21 (10) : 1191 - 1194
  • [47] An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions
    Zhang, Xin Ying
    Qu, Ying Ying
    Sen Fan, Xue
    CHINESE CHEMICAL LETTERS, 2010, 21 (10) : 1191 - 1194
  • [48] One-pot protocol for the reductive amination of aldehydes using thiamine hydrochloride as a green catalyst under solvent-free condition
    Patil, Shripad
    Bedre, Ashwini
    Gade, Vilas
    Jopale, Manohar
    Bhagat, Ravindra
    Pise, Ashok
    SYNTHETIC COMMUNICATIONS, 2023, 53 (18) : 1545 - 1558
  • [49] Clean and simple chemoselective reduction of imines to amines using boric acid-activated sodium borohydride under solvent-free conditions
    Cho, BT
    Kang, SK
    SYNLETT, 2004, (09) : 1484 - 1488
  • [50] Effect of Microwave Radiation on the Solvent-free Synthesis of Phthaloylamino Acids
    Pankrushina, Natalia A.
    Korotkikh, Mikhail O.
    Mikheev, Alexander N.
    CURRENT MICROWAVE CHEMISTRY, 2023, 10 (01) : 60 - 65
12345