A Durable Relationship: Respiratory Syncytial Virus Bronchiolitis and Asthma past Their Golden Anniversary

被引：25
作者：
Esteban, Ignacio [1 ,2 ]
Stein, Renato T. [3 ]
Polack, Fernando P. [1 ,4 ]
机构：
[1] Fdn INFANT, RA-1406 Buenos Aires, DF, Argentina
[2] Hosp Pediat Prof Dr Juan P Garrahan, RA-1245 Buenos Aires, DF, Argentina
[3] Pontificia Univ Catolica Rio Grande do Sul, Ctr INFANT, BR-90610000 Porto Alegre, RS, Brazil
[4] Vanderbilt Univ, Dept Pediat, Nashville, TN 37240 USA
来源：
VACCINES | 2020年 / 8卷 / 02期
关键词：
respiratory syncytial virus; bronchiolitis; asthma; wheezing; LUNG-FUNCTION; PALIVIZUMAB PROPHYLAXIS; EARLY-LIFE; CHILDHOOD ASTHMA; IMMUNE-RESPONSE; FUNCTION ABNORMALITIES; BRONCHIAL REACTIVITY; VIRAL BRONCHIOLITIS; PULMONARY-FUNCTION; PERIPHERAL-BLOOD;
D O I：
10.3390/vaccines8020201
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Numerous preventive strategies against respiratory syncytial virus (RSV) are undergoing late stage evaluation in humans and, in addition to their intended benefit for acute illness, may impact long term consequences of infection in infants. Severe RSV infection has been repeatedly associated in the literature with long term complications, including impaired lung function, recurrent wheezing, and asthma. However, whether RSV lower respiratory tract infection (LRTI) causally affects the odds for developing wheezing and/or asthma during childhood requires further study, and the biological mechanisms underlying this hypothetical progression from viral illness to chronic lung disease are poorly characterized. In this review, we summarize the literature exploring the association between RSV LRTI in infancy and subsequent recurrent wheezing and pediatric asthma.
引用
收藏
页数：10
相关论文
共 83 条
[1]   IL-8 and neutrophil elastase levels in the respiratory tract of infants with RSV bronchiolitis [J].
Abu-Harb, M ;
Bell, F ;
Finn, A ;
Rao, WH ;
Nixon, L ;
Shale, D ;
Everard, ML .
EUROPEAN RESPIRATORY JOURNAL, 1999, 14 (01) :139-143
[2]   Respiratory viral infections in children with asthma: do they matter and can we prevent them? [J].
Ahanchian, Hamid ;
Jones, Carmen M. ;
Chen, Yueh-sheng ;
Sly, Peter D. .
BMC PEDIATRICS, 2012, 12
[3]   Determinants of asthma after severe respiratory syncytial virus bronchiolitis [J].
Bacharier, Leonard B. ;
Cohen, Rebecca ;
Schweiger, Toni ;
Yin-DeClue, Huiquing ;
Christie, Chandrika ;
Zheng, Jie ;
Schechtman, Kenneth B. ;
Strunk, Robert C. ;
Castro, Mario .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 130 (01) :91-+
[4]   Asthma and lung function in adulthood after a viral wheezing episode in early childhood [J].
Backman, K. ;
Ollikainen, H. ;
Piippo-Savolainen, E. ;
Nuolivirta, K. ;
Korppi, M. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2018, 48 (02) :138-146
[5]   Elevated IL-3 and IL-12p40 levels in the lower airway of infants with RSV-induced bronchiolitis correlate with recurrent wheezing [J].
Bertrand, Pablo ;
Lay, Margarita K. ;
Piedimonte, Giovanni ;
Brockmann, Pablo E. ;
Palavecino, Christian E. ;
Hernandez, Jury ;
Leon, Miguel A. ;
Kalergis, Alexis M. ;
Bueno, Susan M. .
CYTOKINE, 2015, 76 (02) :417-423
[6]   RISK-FACTORS FOR WHEEZING DURING INFANCY - A STUDY OF 5953 INFANTS [J].
BISGAARD, H ;
DALGAARD, P ;
NYBOE, J .
ACTA PAEDIATRICA SCANDINAVICA, 1987, 76 (05) :719-726
[7]   Interaction between Asthma and Lung Function Growth in Early Life [J].
Bisgaard, Hans ;
Jensen, Signe M. ;
Bonnelykke, Klaus .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2012, 185 (11) :1183-1189
[8]   Respiratory Syncytial Virus and Recurrent Wheeze in Healthy Preterm Infants [J].
Blanken, Maarten O. ;
Rovers, Maroeska M. ;
Molenaar, Jorine M. ;
Winkler-Seinstra, Pauline L. ;
Meijer, Adam ;
Kimpen, Jan L. L. ;
Bont, Louis .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (19) :1791-1799
[9]   Respiratory syncytial virus infection in Navajo and White Mountain Apache children [J].
Bockova, J ;
O'Brien, KL ;
Oski, J ;
Croll, J ;
Reid, R ;
Weatherholtz, RC ;
Santosham, M ;
Karron, RA .
PEDIATRICS, 2002, 110 (02) :e20
[10]  
Bozaykut Abdulkadir, 2013, J Clin Med Res, V5, P395, DOI 10.4021/jocmr1543w
123456789