Ewing's sarcoma of the cervix: a case report and review of literature

被引：1

作者：

Zhang, Yangyang ^{[1
,2
]}

Nong, Weixia ^{[5
]}

Ren, Yan ^{[1
,2
]}

Jiang, Jinfang ^{[1
,2
]}

Zhang, Haijun ^{[1
,2
]}

Meng, Lian ^{[1
,2
]}

Li, Qianru ^{[1
,2
]}

Zhang, Qiaochu ^{[1
,2
]}

Wang, Xiaomeng ^{[1
,2
]}

Wang, Yang ^{[1
,2
]}

Liu, Chunxia ^{[1
,2
]}

Li, Feng ^{[1
,2
,3
,4
]}

机构：

[1] Shihezi Univ, Dept Pathol, Sch Med, Shihezi 832002, Xinjiang, Peoples R China

[2] Chinese Minist Educ, Key Labs Xinjiang Endem & Ethn Dis, Shihezi 832002, Xinjiang, Peoples R China

[3] Capital Med Univ, Beijing Chaoyang Hosp, Dept Pathol, Beijing 100020, Peoples R China

[4] Capital Med Univ, Med Reaearch Ctr, Beijing, Peoples R China

[5] Shihezi Univ, Dept Hematol, Affiliated Hosp 1, Med Coll, Shihezi, Xinjiang, Peoples R China

来源：

HISTOLOGY AND HISTOPATHOLOGY | 2020年 / 35卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Ewing's sarcoma (ES); Cervical; Gene arrangement; PRIMITIVE NEUROECTODERMAL TUMOR; UTERINE CERVIX;

D O I：

10.14670/HH-18-181

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Ewing's sarcoma (ES) is a small cell malignant tumor that occurs in the bone of children or adolescents. ES can also occur in extraskeletal organs, such as the pancreas, thyroid, liver, proximal phalanx, and, rarely, cervix. Only 15 published case reports have discussed ES arising in the cervix. We report a 76-year-old woman who had groin mass. ES was diagnosed in accordance with morphological and immunohistochemical maps. Fluorescence in situ hybridization and RT-PCR (reverse transcription PCR) revealed ESWR1 gene rearrangement and fusion gene formation (EWS-FLI-1), both of which confirmed the diagnosis of ES. Although the patient underwent surgical resection, the patient died without chemotherapy and radiotherapy. This case is the first one to involve a patient aged over 70 years and the fifth one to show metastasis occurrence.

引用

页码：475 / 480

页数：6