Synthesis of Pyrimidopyrimidinediones in a Deep Eutectic Reaction Mixture

被引：22

作者：

Gore, Sangram ^{[1
,2
]}

Baskaran, Sundarababu ^{[1
]}

Koenig, Burkhard ^{[2
]}

机构：

[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India

[2] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 13期

关键词：

eutectic mixtures; glycoluril; low melting mixtures; pyrimidopyrimidinediones; sustainable chemistry; UREA-SALT MIXTURES; SUBSTITUTED GLYCOLURILS; CUCURBITURIL HOMOLOGS; ACID; SOLVENTS; CONDENSATION; PYRIMIDINES; ANALOGS; FACILE;

D O I：

10.1002/adsc.201200257

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An efficient and general synthesis of hexahydropyrimidopyrimidinediones has been developed employing a low melting L-(+)-tartaric acid-dimethylurea mixture as reaction medium. The melt acts at the same time as solvent, catalyst and reactant. Functionalized hexahydropyrimidopyrimidinediones are obtained in good to excellent yields after simple work-up.

引用

页码：2368 / 2372

页数：5

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