Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

被引：71

作者：

Kim, Minjeong ^{[1
]}

Ko, Sung-Kyun ^{[1
]}

Kim, Hyemi ^{[1
]}

Shin, Injae ^{[1
]}

Tae, Jinsung ^{[1
]}

机构：

[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 72期

关键词：

REACTIVE OXYGEN; IN-VIVO; COUMARIN;

D O I：

10.1039/c3cc44627a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new rhodamine fluorescent probe for monitoring (OH)-O-center dot has been developed based on the oxidative C-H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for (OH)-O-center dot with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular (OH)-O-center dot in live cells.

引用

页码：7959 / 7961

页数：3

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