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Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals
被引:71
|作者:
Kim, Minjeong
[1
]
Ko, Sung-Kyun
[1
]
Kim, Hyemi
[1
]
Shin, Injae
[1
]
Tae, Jinsung
[1
]
机构:
[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
关键词:
REACTIVE OXYGEN;
IN-VIVO;
COUMARIN;
D O I:
10.1039/c3cc44627a
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
A new rhodamine fluorescent probe for monitoring (OH)-O-center dot has been developed based on the oxidative C-H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for (OH)-O-center dot with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular (OH)-O-center dot in live cells.
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页码:7959 / 7961
页数:3
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