Presentation of Severe Acute Respiratory Syndrome-Coronavirus 2 Infection as Cholestatic Jaundice in Two Healthy Adolescents

被引:13
作者
Perez, Adriana [1 ]
Kogan-Liberman, Debora [1 ]
Sheflin-Findling, Shari [2 ]
Raizner, Aileen [1 ]
Ahuja, Kanya L. [2 ]
Ovchinsky, Nadia [1 ]
机构
[1] Childrens Hosp Montefiore, Albert Einstein Coll Med, Dept Pediat, Div Gastroenterol Hepatol & Nutr, Bronx, NY 10467 USA
[2] Steven & Alexandra Cohen Childrens Med Ctr New Yo, Zucker Sch Med Hofstra Northwell, Dept Pediat, Div Pediat Gastroenterol Liver Dis & Nutr, Bronx, NY USA
关键词
D O I
10.1016/j.jpeds.2020.07.054
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Liver abnormalities in severe acute respiratory syndrome-coronavirus 2 infection, including hepatitis and cholestasis, have been observed in adults and are associated with worse outcomes. We describe 2 adolescents with cholestasis and hepatitis with mild presentation of severe acute respiratory syndrome-coronavirus 2 lacking typical symptoms. Our intention is to raise index of suspicion for testing and protective equipment use.
引用
收藏
页码:278 / 280
页数:3
相关论文
共 20 条
[1]  
[Anonymous], 2020, Associated General Contractors of America
[2]   Cholangiocyte pathobiology [J].
Banales, Jesus M. ;
Huebert, Robert C. ;
Karlsen, Tom ;
Strazzabosco, Mario ;
LaRusso, Nicholas F. ;
Gores, Gregory J. .
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2019, 16 (05) :269-281
[3]  
CDC, COR DIS 2019 COVID 1
[4]  
CDC. National Center for Health Statistics, PROV DEATH COUNTS CO
[5]  
Chai X, 2020, SPECIFIC ACE2 EXPRES, V2020
[6]   A 55-Day-Old Female Infant Infected With 2019 Novel Coronavirus Disease: Presenting With Pneumonia, Liver Injury, and Heart Damage [J].
Cui, Yuxia ;
Tian, Maolu ;
Huang, Dong ;
Wang, Xike ;
Huang, Yuying ;
Fan, Li ;
Wang, Liang ;
Chen, Yun ;
Liu, Wenpu ;
Zhang, Kai ;
Wu, Yue ;
Yang, Zhenzhong ;
Tao, Jing ;
Feng, Jie ;
Liu, Kaiyu ;
Ye, Xianwei ;
Wang, Rongpin ;
Zhang, Xiangyan ;
Zha, Yan .
JOURNAL OF INFECTIOUS DISEASES, 2020, 221 (11) :1775-1781
[7]   Host Factors in Coronavirus Replication [J].
de Wilde, Adriaan H. ;
Snijder, Eric J. ;
Kikkert, Marjolein ;
van Hemert, Martijn J. .
ROLES OF HOST GENE AND NON-CODING RNA EXPRESSION IN VIRUS INFECTION, 2018, 419 :1-42
[8]   Epidemiology of COVID-19 Among Children in China [J].
Dong, Yuanyuan ;
Mo, Xi ;
Hu, Yabin ;
Qi, Xin ;
Jiang, Fan ;
Jiang, Zhongyi ;
Tong, Shilu .
PEDIATRICS, 2020, 145 (06)
[9]   Inherited Disorders of Bilirubin Transport and Conjugation: New Insights Into Molecular Mechanisms and Consequences [J].
Erlinger, Serge ;
Arias, Irwin M. ;
Dhumeaux, Daniel .
GASTROENTEROLOGY, 2014, 146 (07) :1625-1638
[10]   Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [J].
Huang, Chaolin ;
Wang, Yeming ;
Li, Xingwang ;
Ren, Lili ;
Zhao, Jianping ;
Hu, Yi ;
Zhang, Li ;
Fan, Guohui ;
Xu, Jiuyang ;
Gu, Xiaoying ;
Cheng, Zhenshun ;
Yu, Ting ;
Xia, Jiaan ;
Wei, Yuan ;
Wu, Wenjuan ;
Xie, Xuelei ;
Yin, Wen ;
Li, Hui ;
Liu, Min ;
Xiao, Yan ;
Gao, Hong ;
Guo, Li ;
Xie, Jungang ;
Wang, Guangfa ;
Jiang, Rongmeng ;
Gao, Zhancheng ;
Jin, Qi ;
Wang, Jianwei ;
Cao, Bin .
LANCET, 2020, 395 (10223) :497-506