Remarkable Functional Convergence: Alarmone ppGpp Mediates Persistence by Activating Type I and II Toxin-Antitoxins

被引:13
作者
Gerdes, Kenn [1 ]
Maisonneuve, Etienne [1 ]
机构
[1] Univ Copenhagen, Dept Biol, DK-2200 Copenhagen N, Denmark
关键词
BACTERIAL; BISTABILITY; OBG;
D O I
10.1016/j.molcel.2015.06.019
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Molecular Cell, Verstraeten et al. (2015) demonstrate that the conserved GTPase Obg and the second messenger ppGpp mediate persistence by activation of a type I toxin-antitoxin module (hokB/sokB) in E. coli.
引用
收藏
页码:1 / 3
页数:3
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