Chemical tags: inspiration for advanced imaging techniques

被引：29
|
作者：
Chen, Zhixing [1 ]
Cornish, Virginia W. [1 ]
Min, Wei [1 ]
机构：
[1] Columbia Univ, Dept Chem, New York, NY 10027 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2013年 / 17卷 / 04期
关键词：
LIVING CELLS; STIMULATED-EMISSION; BETA-LACTAMASE; PROTEIN; MICROSCOPY; FLUOROPHORE; MULTICOLOR; MOLECULES; TRACKING; PROBES;
D O I：
10.1016/j.cbpa.2013.05.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review summarizes recent applications of chemical tags in conjunction with advanced bio-imaging techniques including single-molecule fluorescence, spatiotemporally resolved ensemble microscopy techniques, and imaging modalities beyond fluorescence. We aim to illustrate the unique advantages of chemical tags in facilitating contemporary microscopy to address biological problems that are difficult or near impossible to approach otherwise. We hope our review will inspire more innovative applications enabled by the mingling of these two growing fields.
引用
收藏
页码：637 / 643
页数：7
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