EPR investigation of damage centers formed in some drug powders irradiated with gamma rays

被引：3
|
作者：
Sutcu, Kerem [1 ]
机构：
[1] Dicle Univ, Fac Educ, Dept Sci Educ, Diyarbakir, Turkey
来源：
JOURNAL OF MOLECULAR STRUCTURE | 2018年 / 1163卷
关键词：
EPR; Free radicals; Drugs; gamma-irradiation; ELECTRON-SPIN-RESONANCE; RADIATION STERILIZATION; PARAMAGNETIC-RESONANCE; RADICALS; ACID; IDENTIFICATION; ESR;
D O I：
10.1016/j.molstruc.2018.02.101
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The radiation damage centers in levetiracetam, progesterone, ethosuximide, and propranolol hydrochloride were investigated by EPR spectroscopy at 295 K. The paramagnetic species were attributed to the -CHCHNH-, -CH2CH2CH- and -CH-, -CHCH2N- and -CH-, and -NCCH2- radicals, respectively. The results were observed as being in good conformity with the literature. The spectra of these compounds were computer simulated. Furthermore, the EPR parameters of the radicals formed by (SIC)-irradiation in the samples were determined. (C) 2018 Elsevier B.V. All rights reserved.
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页码：1 / 3
页数：3
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