EPR investigation of damage centers formed in some drug powders irradiated with gamma rays

被引：3

作者：

Sutcu, Kerem ^{[1
]}

机构：

[1] Dicle Univ, Fac Educ, Dept Sci Educ, Diyarbakir, Turkey

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2018年 / 1163卷

关键词：

EPR; Free radicals; Drugs; gamma-irradiation; ELECTRON-SPIN-RESONANCE; RADIATION STERILIZATION; PARAMAGNETIC-RESONANCE; RADICALS; ACID; IDENTIFICATION; ESR;

D O I：

10.1016/j.molstruc.2018.02.101

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The radiation damage centers in levetiracetam, progesterone, ethosuximide, and propranolol hydrochloride were investigated by EPR spectroscopy at 295 K. The paramagnetic species were attributed to the -CHCHNH-, -CH2CH2CH- and -CH-, -CHCH2N- and -CH-, and -NCCH2- radicals, respectively. The results were observed as being in good conformity with the literature. The spectra of these compounds were computer simulated. Furthermore, the EPR parameters of the radicals formed by (SIC)-irradiation in the samples were determined. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：1 / 3

页数：3

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