Rare Case of Endoscopic Treatment for Bevacizumab-Related Gastric Perforation in a Patient with Ovarian Cancer

被引：1
|
作者：
Cappuccio, Serena [1 ]
Marinucci, Benito [2 ]
Bove, Vincenzo [3 ]
Turco, Luigi Carlo [4 ,5 ]
Cosentino, Francesco [5 ]
Scambia, Giovanni [1 ,2 ]
Costamagna, Guido [2 ,3 ]
Boskoski, Ivo [2 ,3 ]
机构：
[1] Fdn Policlin Univ A Gemelli IRCCS, Dept Womans Childs & Publ Hlth, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Fac Med & Chirurg, Rome, Italy
[3] Fdn Policlin Univ Agostino Gemelli IRCCS, Digest Endoscopy Unit, Rome, Italy
[4] Mater Olbia Spa, Gynecol & Breast Care Unit, Olbia, Italy
[5] Univ Cattolica Sacro Cuore, Gynecol Oncol, Gemelli Molise Spa, Campobasso, Italy
来源：
CHEMOTHERAPY | 2020年 / 65卷 / 1-2期
关键词：
Adverse events; Bevacizumab; Endoscopic suture; Gastric perforation; Ovarian cancer; GASTROINTESTINAL PERFORATION; PHASE-3; TRIAL; CHEMOTHERAPY; THERAPY; RISK; COMBINATION; FOCUS;
D O I：
10.1159/000508556
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Antiangiogenic chemotherapy is a common treatment option for patients with advanced ovarian cancer (OC) and has been proven to be effective and generally safe. Nevertheless, in rare cases, these drugs can give serious complications such as gastrointestinal perforations that can be even mortal or very difficult to treat and can heavily impact the clinical management. We present a rare case of bevacizumab-induced gastric perforation in a patient with advanced OC occurred during bevacizumab-including chemotherapy in an adjuvant setting. Surgical treatment was not possible due to the frailty of the clinical condition of the patient and the gastric perforation was successfully treated with endoscopic suturing.
引用
收藏
页码：54 / 57
页数：4
相关论文
共 50 条
  • [21] Bevacizumab in the Treatment of Ovarian Cancer
    Florian Heitz
    Philipp Harter
    Jana Barinoff
    Bianca Beutel
    Paevi Kannisto
    Jacek P. Grabowski
    Julia Heitz
    Christian Kurzeder
    Andreas du Bois
    Advances in Therapy, 2012, 29 : 723 - 735
  • [22] Bevacizumab in Treatment of High-Risk Ovarian Cancer-A Cost-Effectiveness Analysis
    Chan, John K.
    Herzog, Thomas J.
    Hu, Lilian
    Monk, Bradley J.
    Kiet, Tuyen
    Blansit, Kevin
    Kapp, Daniel S.
    Yu, Xinhua
    ONCOLOGIST, 2014, 19 (05) : 523 - 527
  • [23] Spontaneous renal pelvic perforation in a patient with advanced lung cancer receiving avastin (bevacizumab). About a case
    Salvador, Nicolas
    Cardozo, Andy
    Rafael Espinoza, Alessandri
    ARCHIVOS ESPANOLES DE UROLOGIA, 2020, 73 (01): : 68 - 70
  • [24] Recurrent colon perforation after discontinuation of bevacizumab for ovarian cancer
    Nonaka, Michiko
    Sato, Seiya
    Osaku, Daiken
    Sawada, Mayumi
    Kudoh, Akiko
    Chikumi, Jun
    Sato, Shinya
    Oishi, Tetsuro
    Harada, Tasuku
    GYNECOLOGIC ONCOLOGY REPORTS, 2018, 26 : 21 - 23
  • [25] Wound Complications after Bevacizumab Treatment in Patients Operated on for Ovarian Cancer
    Koskas, Martin
    Chereau, Elisabeth
    Ballester, Marcos
    Selle, Frederic
    Rouzier, Roman
    Darai, Emile
    ANTICANCER RESEARCH, 2010, 30 (11) : 4743 - 4747
  • [26] Bevacizumab beyond progression: Impact of subsequent bevacizumab re-treatment in patients with ovarian, fallopian tube, and peritoneal cancer after progression
    Asare, Amma
    Previs, Rebecca Ann
    Spinosa, Daniel
    Fellman, Bryan
    Scott, Amelia L.
    Mulder, Isabelle
    Mahmoud, Y.
    Enbaya, Ahmed
    Siedel, Jean Hansen
    Cobb, Lauren
    Solima, Pamela T.
    Sood, Anil K.
    Coleman, Robert L.
    Secord, Angeles Alvarez
    Westin, Shannon N.
    GYNECOLOGIC ONCOLOGY, 2025, 194 : 112 - 118
  • [27] Intestinal Perforation: A Rare Complication of Treatment With Bevacizumab
    Adhikari, Ramesh
    Ghose, Medha
    Tekin, Aysun
    Singh, Simranjit
    Singh, Romil
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (03)
  • [28] Bevacizumab treatment and quality of life in advanced ovarian cancer
    Canevari, Silvana
    Raspagliesi, Francesco
    Lorusso, Domenica
    FUTURE ONCOLOGY, 2013, 9 (07) : 951 - 954
  • [29] Spontaneous nasal perforation in a bevacizumab-treated patient with metastatic breast cancer
    Rodriguez, Cesar A.
    Martin, Teresa
    Lozano, Rebeca
    Gomez, Amalia
    Cruz, Juan J.
    BREAST JOURNAL, 2017, 23 (06) : 745 - 746
  • [30] Autopsy and Cardiac Magnetic Resonance Image Case of Bevacizumab-Related Cardiomyopathy
    Hashimoto, Naoki
    Kitano, Daisuke
    Tamaki, Takehiro
    Koyama, Yutaka
    Yamada, Akimasa
    Hatakeyama, Kinta
    Hao, Hiroyuki
    Okumura, Yasuo
    JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 2022, 9 (07)
12345