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McMaster Univ, Schroeder Allergy & Immunol Res Inst, Dept Med, McMaster Immunol Res Ctr, 1280 Main St W, Hamilton, ON L8S 4L8, Canada McMaster Univ, Schroeder Allergy & Immunol Res Inst, Dept Med, McMaster Immunol Res Ctr, 1280 Main St W, Hamilton, ON L8S 4L8, Canada