The intussusception antireflux valve is ineffective in preventing cholangitis in biliary atresia

被引:23
|
作者
Sartorelli, KH
Holland, RM
Allshouse, MJ
Karrer, FM
Lilly, JR
机构
[1] UNIV COLORADO,SCH MED,DEPT SURG,DENVER,CO
[2] CHILDRENS HOSP,DENVER,CO 80218
关键词
cholangitis; Kasai procedure; antireflux valve;
D O I
10.1016/S0022-3468(96)90747-2
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Cholangitis is the most common complication after portoenterostomy for biliary atresia. The construction of an intussusception valve in the Roux-en-Y limb of the portoenterostomy has been advocated as a means to ameliorate this complication. The authors reviewed the records of children who underwent portoenterostomy to assess the incidence and severity of cholangitis, as well as outcome. The children were divided into two groups according to whether they did not have (group I) or did have (group II) an antireflux valve in the Roux limb of the bilioenteric conduit. There were 19 children in each group. There were no significant differences between the groups with respect to age at time of portoenterostomy or length of follow-up (Table 1). Nine group I patients are alive and well; five died and five have had or are awaiting transplantation. In group II, 10 patients are alive and well, eight have had transplantation, and one is awaiting transplantation. Outcome with respect to death or the need for liver transplantation because of progressive hepatic failure is not different between the groups (P = 1.0, Fisher's 2 x 2). The incidence of cholangitis was evaluated by comparing the average number of episodes of cholangitis during the follow-up period, the number of episodes per year, and the number of episodes in the first postoperative year (when this complication is most prevalent). Analysis of the data showed no difference in incidence between those with valved and nonvalved biliary conduits. The severity of cholangitis, judged by total length of antibiotic treatment, did not differ between the groups. It appears that the presence of an intussusception valve in the Roux-en-Y biliary conduit does not affect the incidence of cholangitis or the outcome after portoenterostomy, over short-term follow-up. Copyright (C) 1996 by W.B. Saunders Company
引用
收藏
页码:403 / 406
页数:4
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