Cytotoxic limonoids from the root bark of Dictamnus angustifolius

被引:2
作者
Sun, Jian-Bo [1 ]
Tang, Ben-Qin [2 ]
Li, Qiangqiang [1 ]
Wang, Bing [1 ]
Liang, Jing-Yu [1 ]
Chen, Li [1 ]
机构
[1] China Pharmaceut Univ, Dept Nat Med Chem, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China
[2] Shunde Polytech Coll, Dept Med Sci, Shunde 528333, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
Dictamnus angustifolius; Limonoids; Cytotoxic activities; DASYCARPUS; ALKALOIDS;
D O I
10.1016/j.fitote.2016.09.001
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Three novel limonoids, dictangustone G (1), dictangustone H (2), and dictangustone I (3) were isolated from the root bark of Dictamnus angustifolius. Their structures were elucidated on the basis of detailed spectroscopic analysis including UV, IR, HRESIMS, 1D and 2D NMR spectroscopic experiments. Compounds 1-3 were evaluated for their cytotoxic activities using Hela, A549; MCF7, and LN229 cell lines. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:92 / 95
页数:4
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