Synthetic approaches to spiroaminals

被引：41
作者：
Sinibaldi, Marie-Eve [1 ]
Canet, Isabelle [1 ]
机构：
[1] Univ Blaise Pascal, Lab Synth & Etud Syst Interet Biol SEESIB, UMR 6504, F-63177 Aubiere, France
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 26期
关键词：
nitrogen heterocycles; oxygen heterocycles; spiro compounds; synthetic methods;
D O I：
10.1002/ejoc.200800371
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The 1-oxa-7-azaspiro[5.5]undecane, 1-oxa-6-azaspiro[4.5]decane, 1-oxa-7-azaspiro[5.4]decane and 1-oxa-6-azaspiro[4.4]nonane ring systems are found as the cores of natural or synthetic products that possess significant biological activities. Because of their potential applications, together with the novelty of their skeletons, these compounds represent challenging targets for chemical synthesis. In this review we summarize the different strategies developed for the synthesis of these spiroaminals. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008.
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收藏
页码：4391 / 4399
页数：9
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