The cAMP responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down regulation of RhoA activity

被引：0

作者：

Zieba, Bartosz Jakub ^{[1
,2
]}

Artamonov, Mykhaylo V. ^{[2
]}

Jin, Li ^{[2
]}

Momotani, Ko ^{[2
]}

Ho, Ruoya ^{[2
]}

Franke, Aaron S. ^{[2
]}

Neppl, Ronald L. ^{[2
]}

Stevenson, Andra S. ^{[2
]}

Khromov, Alexander S. ^{[2
]}

Chrzanowska-Wodnicka, Magdalena ^{[3
]}

Somlyo, Avril V. ^{[2
]}

机构：

[1] Jagiellonian Univ, Dept Cell Biochem, Krakow, Poland

[2] Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA USA

[3] Blood Ctr SE Wisconsin Inc, Blood Res Inst, Milwaukee, WI 53233 USA

来源：

FASEB JOURNAL | 2011年 / 25卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：1

共 45 条

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[44] Down-regulation of caveolin-1 in smooth muscle from TNBS-induced colitis mediates the increase in phosphodiesterase-5 activity and decrease in cGMP-induced muscle relaxation
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[45] Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor
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