Exhaled Nitric Oxide (FeNO) as a Non-Invasive Marker of Airway Inflammation

被引：61

作者：

Munakata, Mitsuru ^{[1
,2
]}

机构：

[1] Fukushima Med Univ Hosp, Fukushima 9601295, Japan

[2] Fukushima Med Univ, Fukushima 9601295, Japan

来源：

ALLERGOLOGY INTERNATIONAL | 2012年 / 61卷 / 03期

关键词：

asthma; cut-off; diagnosis; monitor; non-invasive; SYNTHASE GENE-EXPRESSION; RELAXING FACTOR; MESSENGER-RNA; SMOOTH-MUSCLE; UP-REGULATION; YOUNG-ADULTS; NERVE-FIBERS; RAT LUNG; ASTHMA; EPITHELIUM;

D O I：

10.2332/allergolint.12-RAI-0461

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Nitric oxide (NO), previously very famous for being an environmental pollutant in the field of pulmonary medicine, is now known as the smallest, lightest, and most famed molecule to act as a biological messenger. Furthermore, recent basic researches have revealed the production mechanisms and physiological functions of nitric oxide in the lung, and clinical researches have been clarifying its tight relation to airway inflammation in asthma. On the bases of this knowledge, fractional nitric oxide (FeNO) has now been introduced as one of the most practical tools for the diagnosis and management of bronchial asthma.

引用

页码：365 / 372

页数：8

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