Direct Phosphorus-Induced Fluoroalkylthiolation with Fluoroalkylsulfonyl Chlorides

被引：67
作者：
Jiang, Lvqi [1 ]
Yi, Wenbin [1 ]
Liu, Qiran [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Chem Engn Coll, 200 Xiao Ling Wei St, Nanjing, Jiangsu, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2016年 / 358卷 / 23期
基金：
中国国家自然科学基金;
关键词：
electron-rich arenes and thiols; fluoroalkylsulfonyl chlorides; fluoroalkylthiolation; phosphorus-induced reaction; HYPERVALENT IODINE REAGENT; ELECTROPHILIC TRIFLUOROMETHYLTHIOLATION; ANTIARRHYTHMICS; FLUORINATION; SULFIDES; EFFICACY; INDOLES; ALKENES; BONDS; ARYL;
D O I：
10.1002/adsc.201600651
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A simple and practical method of fluoroalkylthiolation using fluoroalkylsulfonyl chlorides (RfSO2Cl, R-f=CF3, C4F9, C8F17, CF2H and CH2CF3) has been developed. These easy-to-handle reagents are powerful and can be used for electrophilic fluoroalkylthiolation of electron-rich arenes and thiols using diethyl phosphite as reducing agent.
引用
收藏
页码：3700 / 3705
页数：6
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