Comparative effectiveness research: does one size fit all?

被引：5

作者：

Kunz, Lauren M. ^{[2
]}

Yeh, Robert W. ^{[3
,4
]}

Normand, Sharon-Lise T. ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA

[2] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA

[3] Massachusetts Gen Hosp, Boston, MA 02114 USA

[4] Harvard Clin Res Inst, Boston, MA USA

来源：

STATISTICS IN MEDICINE | 2012年 / 31卷 / 25期

关键词：

ENDARTERECTOMY; ANGIOPLASTY; OUTCOMES;

D O I：

10.1002/sim.5482

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In this commentary, we argue that although randomization has many benefits, not all questions we seek to answer fit into a randomized setting. Our argument utilizes the clinical setting of carotid atherosclerosis management where specific clinical questions are answered by using a variety of comparative effectiveness designs. Observational studies should not be ruled out when designing studies to address questions of comparative effectiveness. Copyright (c) 2012 John Wiley & Sons, Ltd.

引用

页码：3062 / 3065

页数：4

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