Polypyrrole nanoparticles for high-performance in vivo near-infrared photothermal cancer therapy

被引：322
作者：
Chen, Mei
Fang, Xiaoliang
Tang, Shaoheng
Zheng, Nanfeng [1 ]
机构：
[1] Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 71期
关键词：
BIOCOMPATIBILITY; NANOCRYSTALS; ABLATION; AGENT;
D O I：
10.1039/c2cc34463g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Polypyrrole nanoparticles (PPy NPs) exhibit strong absorption in the near infrared (NIR) region. With an excellent photo-thermal efficiency of similar to 45% at 808 nm, sub-100 nm PPy NPs are demonstrated to be a promising photothermal agent for in vivo cancer therapy using NIR irradiation.
引用
收藏
页码：8934 / 8936
页数：3
相关论文
共 24 条
[1]   Polypyrrole Nanoparticles: A Potential Optical Coherence Tomography Contrast Agent for Cancer Imaging [J].
Au, Kin Man ;
Lu, Zenghai ;
Matcher, Stephen J. ;
Armes, Steven P. .
ADVANCED MATERIALS, 2011, 23 (48) :5792-+
[2]   Gold Nanocages as Photothermal Transducers for Cancer Treatment [J].
Chen, Jingyi ;
Glaus, Charles ;
Laforest, Richard ;
Zhang, Qiang ;
Yang, Miaoxian ;
Gidding, Michael ;
Welch, Michael J. ;
Xia, Younan .
SMALL, 2010, 6 (07) :811-817
[3]   Multifunctional polymeric nanoparticles for combined chemotherapeutic and near-infrared photothermal cancer therapy in vitro and in vivo [J].
Cheng, Fong-Yu ;
Su, Chia-Hao ;
Wu, Ping-Ching ;
Yeh, Chen-Sheng .
CHEMICAL COMMUNICATIONS, 2010, 46 (18) :3167-3169
[4]  
Cheng L, 2012, ACS NANO, V6, P5605, DOI [10.1021/nn304719q, 10.1021/nn301539m]
[5]   Tumor Regression In Vivo by Photothermal Therapy Based on Gold-Nanorod-Loaded, Functional Nanocarriers [J].
Choi, Won Il ;
Kim, Ja-Young ;
Kang, Chul ;
Byeon, Clare C. ;
Kim, Young Ha ;
Tee, Giyoong .
ACS NANO, 2011, 5 (03) :1995-2003
[6]   In vivo studies of polypyrrole/peptide coated neural probes [J].
Cui, XY ;
Wiler, J ;
Dzaman, M ;
Altschuler, RA ;
Martin, DC .
BIOMATERIALS, 2003, 24 (05) :777-787
[7]   Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics [J].
George, PM ;
Lyckman, AW ;
LaVan, DA ;
Hegde, A ;
Leung, Y ;
Avasare, R ;
Testa, C ;
Alexander, PM ;
Langer, R ;
Sur, M .
BIOMATERIALS, 2005, 26 (17) :3511-3519
[8]   Copper Selenide Nanocrystals for Photothermal Therapy [J].
Hessel, Colin M. ;
Pattani, Varun P. ;
Rasch, Michael ;
Panthani, Matthew G. ;
Koo, Bonil ;
Tunnell, James W. ;
Korgel, Brian A. .
NANO LETTERS, 2011, 11 (06) :2560-2566
[9]   Plasmonic photothermal therapy (PPTT) using gold nanoparticles [J].
Huang, Xiaohua ;
Jain, Prashant K. ;
El-Sayed, Ivan H. ;
El-Sayed, Mostafa A. .
LASERS IN MEDICAL SCIENCE, 2008, 23 (03) :217-228
[10]  
Huang XQ, 2011, NAT NANOTECHNOL, V6, P28, DOI [10.1038/nnano.2010.235, 10.1038/NNANO.2010.235]
123