Cardiac Manifestations of Systemic Lupus Erythematosus

被引：114

作者：

Miner, Jonathan J. ^{[1
]}

Kim, Alfred H. J. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Med, Div Rheumatol, St Louis, MO 63110 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2014年 / 40卷 / 01期

关键词：

Systemic lupus erythematosus; Neonatal lupus; Congenital heart block; Myocarditis; Pericarditis; Coronary artery disease; Libman-Sacks; CONGENITAL HEART-BLOCK; CONNECTIVE-TISSUE DISEASE; LIBMAN-SACKS ENDOCARDITIS; AORTIC-VALVE-REPLACEMENT; ANTI-RO/SSA ANTIBODIES; CORRECTED QT INTERVAL; NEONATAL LUPUS; RISK-FACTORS; CONSTRICTIVE PERICARDITIS; ANTIPHOSPHOLIPID SYNDROME;

D O I：

10.1016/j.rdc.2013.10.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that manifests with multiorgan inflammation. Cardiac involvement is common, with manifestation that include pericarditis, myocarditis, conduction defects, valvular disease, and coronary artery disease. In addition to cardiac disease in adults with SLE, the children of women with SLE can develop neonatal lupus by passive transfer of autoantibodies across the placenta. This article describes the cardiac manifestations of SLE and highlights some key unanswered questions about the disease and its pathogenesis.

引用

页码：51 / +

页数：12

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