Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambarene, Gabon-a retrospective observational study

被引：11

作者：

Stolp, S. M. ^{[1
,2
]}

Huson, M. A. M. ^{[1
,2
]}

Janssen, S. ^{[1
,2
]}

Beyeme, J. O. ^{[3
]}

Grobusch, M. P. ^{[1
,2
,4
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Infect Dis, Ctr Trop Med & Travel Med, NL-1105 AZ Amsterdam, Netherlands

[2] CERMEL, Lambarene, Gabon

[3] Hop Albert Schweitzer, Dept Med, Lambarene, Gabon

[4] Univ Tubingen, Inst Trop Med, Tubingen, Germany

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2013年 / 19卷 / 11期

关键词：

Central Africa; drug resistance; Gabon; human immunodeficiency virus; tuberculosis;

D O I：

10.1111/1469-0691.12278

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Epidemiological data on tuberculosis in Central Africa are limited. We performed a retrospective observational study on clinical characteristics of 719 hospitalized tuberculosis patients in Lambarene, Gabon. Human immunodeficiency virus (HIV) co-infection rate was high (34%) and in-hospital mortality was significantly higher in HIV-positive patients (10% versus 2%). Long-term information on patient outcome was limited; however, from 2008 to 2011, loss to follow up was noted in 28% of cases. Our data illustrate the high burden of TB in Gabon, where loss to follow up and emerging drug resistance are important problems for which comprehensive data are still lacking.

引用

页码：E499 / E501

页数：3

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