A comprehensive study of small inhomogeneous multilayered rectangular coaxial lines (RCLs) with irregular cross sections is presented in this paper. An accurate and efficient quasi-analytical technique based on numerical implementation of simply and doubly connected Schwarz-Christoffel conformal mapping is utilized for modeling. Misaligned and offset layers, under-over cutting due to etching, nonuniform dielectric support, and other nonidealities due to fabrication of RCLs are studied and their effects on characteristic impedance, attenuation, bandwidth, and powerhandling capacity are discussed. The validity of obtained results is verified with suitable published data, analytical models, and/or finite-element simulations.