The great debate at "Melanoma Bridge 2018", Naples, December 1st, 2018

被引：1

作者：

Ascierto, Paolo A. ^{[1
]}

Bruzzi, Paolo ^{[2
]}

Eggermont, Alexander ^{[4
]}

Hamid, Omid ^{[5
]}

Tawbi, Hussein A. ^{[7
]}

van Akkooi, Alexander ^{[9
]}

Testori, Alessandro ^{[8
]}

Caraco, Corrado ^{[3
]}

Puzanov, Igor ^{[6
]}

Perrone, Francesco ^{[10
]}

机构：

[1] Ist Nazl Tumori IRCCS Fdn G Pascale, Unit Melanoma Canc Immunotherapy & Innovat Therap, Via Mariano Semmola, I-80131 Naples, Italy

[2] Univ Hosp San Martino, Clin Epidemiol Unit, Genoa, Italy

[3] Ist Nazl Tumori IRCCS Fdn G Pascale, Dept Melanoma Soft Tissue Muscle Skeletal & Head, Naples, Italy

[4] Inst Gustave Roussy Villejuif, Paris Sud, Paris, France

[5] Angeles Clin & Res Inst, Clin Res & Immunotherapy, Los Angeles, CA USA

[6] Roswell Pk Comprehens Canc Ctr, Dept Med, Buffalo, NY USA

[7] UT MD Anderson Canc Ctr, Invest Canc Therapeut, Melanoma Med Oncol, Melanoma Clin Res & Early Drug Dev, Houston, TX USA

[8] EORTC Melanoma Grp, Surg Grp, Brussels, Belgium

[9] Netherlands Canc Inst Antoni van Leeuwenhoek Hosp, Dept Surg Oncol, Amsterdam, Netherlands

[10] Ist Nazl Tumori IRCCS Fdn G Pascale, Clin Trials Unit, Naples, Italy

来源：

JOURNAL OF TRANSLATIONAL MEDICINE | 2019年 / 17卷

关键词：

Melanoma; Immunotherapy; Anti-PD-1; Anti-CTLA-4; Targeted therapy; BRAF inhibitor; MEK inhibitor; Adjuvant; Neoadjuvant; METASTATIC MELANOMA; STAGE-III; IPILIMUMAB; NIVOLUMAB; SURVIVAL; MULTICENTER; PROGRESSION; THERAPIES;

D O I：

10.1186/s12967-019-1892-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The great debate session at the 2018 Melanoma Bridge congress (November 29-December 1, Naples, Italy) featured counterpoint views from experts on three topical issues in melanoma. These were whether overall survival should still be the main endpoint for clinical trials in melanoma, whether anti-cytotoxic T-lymphocyte-associated antigen (CTLA)-4 is still the optimal choice of drug to use in combination with an anti-programmed death (PD)/PD-ligand (L)-1 agent, and the place of adjuvant versus neoadjuvant therapy in patients with melanoma. These three important debates are summarised in this report.

引用

页数：11

共 45 条

[1] The great debate at “Melanoma Bridge 2018”, Naples, December 1st, 2018
Paolo A. Ascierto
Paolo Bruzzi
Alexander Eggermont
Omid Hamid
Hussein A. Tawbi
Alexander van Akkooi
Alessandro Testori
Corrado Caracò
Igor Puzanov
Francesco Perrone
Journal of Translational Medicine, 17
[2] The "Great Debate" at Melanoma Bridge 2022, Naples, December 1st-3rd, 2022
Ascierto, Paolo A. A.
Blank, Christian
Eggermont, Alexander M. M.
Garbe, Claus
Gershenwald, Jeffrey E. E.
Hamid, Omid
Hauschild, Axel
Luke, Jason J. J.
Mehnert, Janice M. M.
Sosman, Jeffrey A. A.
Tawbi, Hussein A. A.
Mandala, Mario
Testori, Alessandro
Caraco, Corrado
Osman, Iman
Puzanov, Igor
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 21 (01)
[3] Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy)
Ascierto, Paolo A.
Agarwala, Sanjiv S.
Botti, Gerardo
Budillon, Alfredo
Davies, Michael A.
Dummer, Reinhard
Ernstoff, Marc
Ferrone, Soldano
Formenti, Silvia
Gajewski, Thomas F.
Garbe, Claus
Hamid, Omid
Lo, Roger S.
Luke, Jason J.
Michielin, Oliver
Palmieri, Giuseppe
Zitvogel, Laurence
Marincola, Francesco M.
Masucci, Giuseppe
Caraco, Corrado
Thurin, Magdalena
Puzanov, Igor
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17 (1)
[4] The Great Debate at "Melanoma Bridge", Naples, December 7th, 2019
Ascierto, Paolo A.
Agarwala, Sanjiv S.
Eggermont, Alexander
Gershenwald, Jeffrey E.
Grob, Jean-Jacques
Hamid, Omid
Michielin, Olivier
Postow, Michael
Puzanov, Igor
Zarour, Hassane M.
Caraco, Corrado
Testori, Alessandro
JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18 (01)
[5] The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022
Paolo A. Ascierto
Christian Blank
Alexander M. Eggermont
Claus Garbe
Jeffrey E. Gershenwald
Omid Hamid
Axel Hauschild
Jason J. Luke
Janice M. Mehnert
Jeffrey A. Sosman
Hussein A. Tawbi
Mario Mandalà
Alessandro Testori
Corrado Caracò
Iman Osman
Igor Puzanov
Journal of Translational Medicine, 21
[6] Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th–1 December 1st, 2018, Naples, Italy)
Paolo A. Ascierto
Sanjiv S. Agarwala
Gerardo Botti
Alfredo Budillon
Michael A. Davies
Reinhard Dummer
Marc Ernstoff
Soldano Ferrone
Silvia Formenti
Thomas F. Gajewski
Claus Garbe
Omid Hamid
Roger S. Lo
Jason J. Luke
Oliver Michielin
Giuseppe Palmieri
Laurence Zitvogel
Francesco M. Marincola
Giuseppe Masucci
Corrado Caracò
Magdalena Thurin
Igor Puzanov
Journal of Translational Medicine, 17
[7] The Great Debate at “Melanoma Bridge”, Naples, December 7th, 2019
Paolo A. Ascierto
Sanjiv S. Agarwala
Alexander Eggermont
Jeffrey E. Gershenwald
Jean-Jacques Grob
Omid Hamid
Olivier Michielin
Michael Postow
Igor Puzanov
Hassane M. Zarour
Corrado Caracò
Alessandro Testori
Journal of Translational Medicine, 18
[8] Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy)
Ascierto, Paolo A.
Agarwala, Sanjiv S.
Warner, Allison Betof
Ernstoff, Marc S.
Fox, Bernard A.
Gajewski, Thomas F.
Galon, Jerome
Garbe, Claus
Gastman, Brian R.
Gershenwald, Jeffrey E.
Kalinski, Pawel
Krogsgaard, Michelle
Leidner, Rom S.
Lo, Roger S.
Menzies, Alexander M.
Michielin, Olivier
Poulikakos, Poulikos I.
Weber, Jeffrey S.
Caraco, Corrado
Osman, Iman
Puzanov, Igor
Thurin, Magdalena
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 21 (01)
[9] Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st–3rd, 2022—Naples, Italy)
Paolo A. Ascierto
Sanjiv S. Agarwala
Allison Betof Warner
Marc S. Ernstoff
Bernard A. Fox
Thomas F. Gajewski
Jérôme Galon
Claus Garbe
Brian R. Gastman
Jeffrey E. Gershenwald
Pawel Kalinski
Michelle Krogsgaard
Rom S. Leidner
Roger S. Lo
Alexander M. Menzies
Olivier Michielin
Poulikos I. Poulikakos
Jeffrey S. Weber
Corrado Caracò
Iman Osman
Igor Puzanov
Magdalena Thurin
Journal of Translational Medicine, 21
[10] The “Great Debate” at Melanoma Bridge 2020: December, 5th, 2020
Paolo A. Ascierto
Michael B. Atkins
Alexander M. Eggermont
Jeffrey E. Gershenwald
Jean-Jacques Grob
Omid Hamid
Vernon K. Sondak
Jeffrey A. Sosman
Hussein A. Tawbi
Jeffrey S. Weber
Corrado Caracò
Iman Osman
Igor Puzanov
Journal of Translational Medicine, 19

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