Multifunctional Silver Nanoparticles-Decorated Silica Functionalized with Retinoic Acid with Anti-Proliferative and Antimicrobial Properties

被引：4

作者：

Tudose, Madalina ^{[1
]}

Culita, Daniela C. ^{[1
]}

Musuc, Adina M. ^{[1
]}

Marinescu, Gabriela ^{[1
]}

Somacescu, Simona ^{[1
]}

Munteanu, Cornel ^{[1
]}

Bleotu, Coralia ^{[2
]}

Chifiriuc, Mariana C. ^{[3
,4
]}

机构：

[1] Romanian Acad, Inst Phys Chem Ilie Murgulescu, Bucharest 060021, Romania

[2] St S Nicolau Virol Inst, 285 Mihai Bravu Ave,Sect 3,77,POB 201, Bucharest 030304, Romania

[3] Univ Bucharest, Fac Biol, Dept Microbiol Immunol, Aleea Portocalelor 1-3, Bucharest, Romania

[4] Univ Bucharest, Res Inst, Spl Independentei 91-95, Bucharest, Romania

来源：

JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2016年 / 26卷 / 05期

关键词：

Composites; Retinoic acid; Chemical synthesis; Transmission electron microscopy; Thermogravimetric analysis; GRAM-NEGATIVE BACTERIA; CELL-LINES; ALL-TRANS; GROWTH; DIFFERENTIATION; STIMULATION; AGENTS; DEATH;

D O I：

10.1007/s10904-016-0407-6

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The paper describes a rapid and simple method for preparing a multifunctional biomaterial based on retinoic acid covalently bound on silica@Ag particles. Monodispersed SiO2 particles were prepared by Stober method and further used for loading the Ag nanoparticles on their surface. This composite was further functionalized with retinoic acid. Characterization of the hybrid materials was made by UV-Visible spectroscopy, Transmission electron microscopy, Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and Thermal analysis. The biological evaluation of the obtained materials revealed their potential use for multiple biomedical applications, from anti-proliferative agents to novel antimicrobial and antibiofilm strategies.

引用

页码：1043 / 1052

页数：10

共 17 条

[1] Multifunctional Silver Nanoparticles-Decorated Silica Functionalized with Retinoic Acid with Anti-Proliferative and Antimicrobial Properties
Madalina Tudose
Daniela C. Culita
Adina M. Musuc
Gabriela Marinescu
Simona Somacescu
Cornel Munteanu
Coralia Bleotu
Mariana C. Chifiriuc
Journal of Inorganic and Organometallic Polymers and Materials, 2016, 26 : 1043 - 1052
[2] Anti-proliferative effects of gold nanoparticles functionalized with Semaphorin 3F
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[3] Acriflavine-loaded solid lipid nanoparticles: preparation, physicochemical characterization, and anti-proliferative properties
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[4] Proliferative and anti-proliferative effects of retinoic acid at doses similar to endogenous levels in Leydig MLTC-1/R2C/TM-3 cells
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MOLECULAR CANCER, 2009, 8
[7] Prdm12 Is Induced by Retinoic Acid and Exhibits Anti-proliferative Properties through the Cell Cycle Modulation of P19 Embryonic Carcinoma Cells
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[8] Multifunctional chitosan/gelatin@tannic acid cryogels decorated with in situ reduced silver nanoparticles for wound healing
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[9] BIOEVALUATION OF THE ANTIMICROBIAL AND ANTI-PROLIFERATIVE POTENTIAL OF SOME DERIVATIVES OF 3,5-DINITRO-4-METHOXYAMINO-BENZOIC ACID
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[10] Silver Nanoparticles Functionalized With Antimicrobial Polypeptides: Benefits and Possible Pitfalls of a Novel Anti-infective Tool
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FRONTIERS IN MICROBIOLOGY, 2021, 12

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