Mutated COVID-19 may foretell a great risk for mankind in the future

被引：93

作者：

Dawood, A. A. ^{[1
]}

机构：

[1] Univ Mosul, Coll Med, Mosul, Iraq

来源：

NEW MICROBES AND NEW INFECTIONS | 2020年 / 35卷

关键词：

COVID-19; Middle-East respiratory syndrome; outbreaks; severe acute respiratory syndrome; zoonotic;

D O I：

10.1016/j.nmni.2020.100673

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Coronavirus disease 2019 SARS-CoV-2 (COVID-19) is a zoonotic virus causing a variety of severe respiratory diseases. SARS-CoV-2 is closest to SARS-CoV and MERS-CoV in structure. The high prevalence of COVID-19 is a result of a lack of symptoms at onset. Our study aimed to present an overview of the virus in terms of structure, epidemiology, symptoms, treatment and prevention. Whole genome sequences and some viral proteins were investigated to determine gaps and changes in alternation of nucleotides and amino acid sequences. We evaluate 11 complete genome sequences of different coronaviruses using BAST and MAFFT software. We also selected seven types of structural proteins. We conclude that COVID-19 might produce new mutations, specifically in glycoproteins, so caution and complete preparation by health authorities is required.

引用

页数：8

共 18 条

[1]

[Anonymous], 2020, LANCET, V395, P922, DOI 10.1016/S0140-6736(20)30644-9

[2]

[Anonymous], 2020, LANCET, DOI [10.1016/S0140-6736(20)30681-4, DOI 10.1016/S0140-6736(20)30681-4]

[3]

Baglivo Mirko, 2020, Acta Biomed, V91, P161, DOI 10.23750/abm.v91i1.9402

[4] Should patients stop their biologic treatment during the COVID-19 pandemic [J].