Simulated pulse response of intracellular structures in biological cells exposed to high-intensity sub-microsecond Pulsed Electric Fields

被引：0
|
作者：
Campbell, RM [1 ]
Crichton, BH [1 ]
Fouracre, RA [1 ]
Judd, MD [1 ]
机构：
[1] Univ Strathclyde, Dept Energy & Environm, High Voltage Technol Grp, Glasgow G1 1XW, Lanark, Scotland
来源：
2005 Annual Report Conference on Electrical Insulation and Dielectric Phenomena | 2005年
关键词：
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Cell response to sub-microsecond Pulsed Electric Fields (sm-PEF) is examined using an equivalent circuit model (ECM) where a network of electrical components is used to represent the cell environment and the cell with its internal structures. The model is evaluated by comparing results with published data from other numerical studies. It is shown that the model, which is not computationally demanding, may be usefully adopted to examine cell and organelle response in vitro, and where the applied pulse shape and frequency spectrum may be of significance.
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页码：377 / 380
页数：4
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