TG4010 A therapeutic vaccine against MUC1 expressing tumors

被引：39
作者：
Limacher, Jean-Marc [1 ]
Quoix, Elisabeth [2 ]
机构：
[1] Transgene SA, Illkirch Graffenstaden, France
[2] Nouvel Hop Civil, Hop Univ Strasbourg, Strasbourg, France
来源：
ONCOIMMUNOLOGY | 2012年 / 1卷 / 05期
关键词：
non-small cell lung cancer; cancer vaccine; TG4010; biomarker; CELL LUNG-CANCER; IMMUNOTHERAPY; CHEMOTHERAPY; MVA-MUC1-IL2;
D O I：
10.4161/onci.19863
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
TG4010 is a therapeutic cancer vaccine based on a viral vector, a modified vaccinia of Ankara (MVA), expressing MUC1 as well as interleukine 2. Today the clinical development is focused on advanced non-small cell lung cancer in combination with first line chemotherapy. Potential biomarkers predictive of activity have been identified.
引用
收藏
页码：791 / 792
页数：2
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