Best supportive care for idiopathic pulmonary fibrosis: current gaps and future directions

被引:36
作者
Ferrara, Giovanni [1 ,2 ,3 ]
Luppi, Fabrizio [4 ]
Birring, Surinder S. [5 ]
Cerri, Stefania [4 ]
Caminati, Antonella [6 ]
Skold, Magnus [1 ,2 ,3 ]
Kreuter, Michael [7 ,8 ]
机构
[1] Karolinska Inst, Sect Resp Med, Dept Med Solna, Stockholm, Sweden
[2] Karolinska Inst, Ctr Mol Med, Stockholm, Sweden
[3] Karolinska Univ Hosp Solna, Div Resp Med & Allergy, Stockholm, Sweden
[4] Univ Hosp Modena, Ctr Rare Lung Dis, Modena, Italy
[5] Kings Coll London, Div Asthma Allergy & Lung Biol, London, England
[6] San Giuseppe Hosp Multimed, Sect Resp Med, Milan, Italy
[7] Heidelberg Univ, Heidelberg, Germany
[8] Heidelberg Univ, Div Resp Med, Ctr Interstitial & Rare Lung Dis, Heidelberg, Germany
关键词
INTERSTITIAL LUNG-DISEASE; QUALITY-OF-LIFE; HEALTH-STATUS; CONTROLLED-TRIAL; CLINICAL-TRIALS; ANTACID THERAPY; PALLIATIVE CARE; CHRONIC COUGH; COPD PATIENTS; K-BILD;
D O I
10.1183/16000617.0076-2017
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Best supportive care (BSC) is generally defined as all the interventions and the multiprofessional approach aimed to improve and optimise quality of life (QoL) in patients affected by progressive diseases. In this sense, it excludes and might be complementary to other interventions directly targeting the disease. BSC improves survival in patients with different types of cancer. Patients with idiopathic pulmonary fibrosis (IPF) experience a vast range of symptoms during the natural history of the disease and might have a beneficial effect of BSC interventions. This review highlights the current evidence on interventions targeting QoL and gaps for the clinical assessment of BSC in the treatment of IPF patients. Very few interventions to improve QoL or improve symptom control are currently supported by well-designed studies. Sound methodology is paramount in evaluating BSC in IPF, as well as the use of validated tools to measure QoL and symptom control in this specific group of patients.
引用
收藏
页数:11
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