Best supportive care for idiopathic pulmonary fibrosis: current gaps and future directions

被引:36
作者
Ferrara, Giovanni [1 ,2 ,3 ]
Luppi, Fabrizio [4 ]
Birring, Surinder S. [5 ]
Cerri, Stefania [4 ]
Caminati, Antonella [6 ]
Skold, Magnus [1 ,2 ,3 ]
Kreuter, Michael [7 ,8 ]
机构
[1] Karolinska Inst, Sect Resp Med, Dept Med Solna, Stockholm, Sweden
[2] Karolinska Inst, Ctr Mol Med, Stockholm, Sweden
[3] Karolinska Univ Hosp Solna, Div Resp Med & Allergy, Stockholm, Sweden
[4] Univ Hosp Modena, Ctr Rare Lung Dis, Modena, Italy
[5] Kings Coll London, Div Asthma Allergy & Lung Biol, London, England
[6] San Giuseppe Hosp Multimed, Sect Resp Med, Milan, Italy
[7] Heidelberg Univ, Heidelberg, Germany
[8] Heidelberg Univ, Div Resp Med, Ctr Interstitial & Rare Lung Dis, Heidelberg, Germany
关键词
INTERSTITIAL LUNG-DISEASE; QUALITY-OF-LIFE; HEALTH-STATUS; CONTROLLED-TRIAL; CLINICAL-TRIALS; ANTACID THERAPY; PALLIATIVE CARE; CHRONIC COUGH; COPD PATIENTS; K-BILD;
D O I
10.1183/16000617.0076-2017
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Best supportive care (BSC) is generally defined as all the interventions and the multiprofessional approach aimed to improve and optimise quality of life (QoL) in patients affected by progressive diseases. In this sense, it excludes and might be complementary to other interventions directly targeting the disease. BSC improves survival in patients with different types of cancer. Patients with idiopathic pulmonary fibrosis (IPF) experience a vast range of symptoms during the natural history of the disease and might have a beneficial effect of BSC interventions. This review highlights the current evidence on interventions targeting QoL and gaps for the clinical assessment of BSC in the treatment of IPF patients. Very few interventions to improve QoL or improve symptom control are currently supported by well-designed studies. Sound methodology is paramount in evaluating BSC in IPF, as well as the use of validated tools to measure QoL and symptom control in this specific group of patients.
引用
收藏
页数:11
相关论文
共 98 条
  • [1] Ahmed N, 2004, COCHRANE DB SYST REV, V3
  • [2] Depression in patients with idiopathic pulmonary fibrosis
    Akhtar, Akhtar A.
    Ali, Mohammad A.
    Smith, Robin P.
    [J]. CHRONIC RESPIRATORY DISEASE, 2013, 10 (03) : 127 - 133
  • [3] [Anonymous], 2013, NICE CLIN GUID
  • [4] [Anonymous], COCHRANE DATABASE SY
  • [5] Exploratory analysis of a phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment
    Azuma, Arata
    Taguchi, Yoshio
    Ogura, Takashi
    Ebina, Masahito
    Taniguchi, Hiroyuki
    Kondoh, Yasuhiro
    Suga, Moritaka
    Takahashi, Hiroki
    Nakata, Koichiro
    Sato, Atsuhiko
    Kudoh, Shoji
    Nukiwa, Toshihiro
    [J]. RESPIRATORY RESEARCH, 2011, 12
  • [6] The dyspnea-anxiety-dyspnea cycle - COPD patients' stories of breathlessness: "It's scary/when you can't breathe"
    Bailey, PH
    [J]. QUALITATIVE HEALTH RESEARCH, 2004, 14 (06) : 760 - 778
  • [7] Measurement of breathlessness in advanced disease: A systematic review
    Bausewein, C.
    Farquhar, M.
    Booth, S.
    Gysels, M.
    Higginson, I. J.
    [J]. RESPIRATORY MEDICINE, 2007, 101 (03) : 399 - 410
  • [8] Understanding Breathlessness: Cross-Sectional Comparison of Symptom Burden and Palliative Care Needs in Chronic Obstructive Pulmonary Disease and Cancer
    Bausewein, Claudia
    Booth, Sara
    Gysels, Marjolein
    Kuehnbach, Robert
    Haberland, Birgit
    Higginson, Irene J.
    [J]. JOURNAL OF PALLIATIVE MEDICINE, 2010, 13 (09) : 1109 - 1118
  • [9] Investigating significant health trends in idiopathic pulmonary fibrosis (INSIGHTS-IPF): rationale, aims and design of a nationwide prospective registry
    Behr, Juergen
    Hoeper, Marius M.
    Kreuter, Michael
    Klotsche, Jens
    Wirtz, Hubert
    Pittrow, David
    [J]. BMJ OPEN RESPIRATORY RESEARCH, 2013, 1 (01):
  • [10] Organisation of diagnosis and treatment of idiopathic pulmonary fibrosis and other interstitial lung diseases in the Nordic countries
    Bendstrup, Elisabeth
    Hyldgaard, Charlotte
    Altraja, Alan
    Sjaheim, Tone
    Myllarniemi, Marjukka
    Gudmundsson, Gunnar
    Skold, Magnus
    Hilberg, Ole
    [J]. EUROPEAN CLINICAL RESPIRATORY JOURNAL, 2015, 2 (01):