Fluorescent chemosensor for biological zinc ions

被引：9

作者：

Bae, Se Won ^{[1
]}

Kim, Eunha ^{[1
,2
]}

Shin, Ik-Soo ^{[1
,3
]}

Park, Seung Bum ^{[1
,2
]}

Hong, Jong-In ^{[1
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea

[2] Seoul Natl Univ, Dept Biophys & Chem Biol, BioMAX Inst, Seoul 151747, South Korea

[3] Soongsil Univ, Dept Chem, Seoul 156743, South Korea

来源：

SUPRAMOLECULAR CHEMISTRY | 2013年 / 25卷 / 01期

关键词：

fluorescent sensor; zinc ion; PeT; cell imaging; MOBILE ZINC; SENSOR; RECOGNITION; APOPTOSIS; SWITCHES; HEALTH; CELLS;

D O I：

10.1080/10610278.2012.720020

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A synthetic fluorescent sensor (sensor 1) is developed using boron-dipyrromethene as a fluorophore and phenoxo-bridged dipicolylamine as a receptor. Sensor 1 shows a significant enhancement of fluorescent intensity and a high selectivity for Zn2+ over various metal cations. The electrochemical study provides a rationale for the fluorescence turn-on of sensor 1 upon complexation with Zn2+ by the blocking of the photo-induced electron transfer mechanism. Sensor 1 can be used to image Zn2+ in A549 cells.

引用

页码：2 / 6

页数：5

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