Air Medical Administration of Tranexamic Acid

被引:1
|
作者
Cornelius, Brian [1 ]
机构
[1] Univ Hlth Shreveport, 1501 Kings Hwy, Shreveport, LA 71103 USA
关键词
Air medical transport; Coagulopathy; Hemorrhage; Tranexamic acid; Trauma; TRAUMATIC INJURY; HEMORRHAGE; OUTCOMES;
D O I
10.1097/JTN.0000000000000259
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Traumatic injury is a significant cause of morbidity and mortality in the United States. Massive hemorrhage is responsible for the vast majority of deaths. Evolution in trauma treatment has resulted in major improvements to emergency care. Tranexamic acid (TXA), an antifibrinolytic agent, is synthetically derived from amino acids. The CRASH-2 study demonstrated that the early administration of TXA results in significant decreases in morbidity and mortality. Experiences by coalition forces in Southwest Asia found a substantial increase in survival of trauma patients with early TXA administration. The PAMPer trial has demonstrated the success of taking plasma to the scene of the incident by helicopter; TXA offers additional benefits when transported by the same means. Air medical utilization of TXA can take battlefield trauma care to the scene of civilian traumatic injuries and save lives.
引用
收藏
页码:30 / 33
页数:4
相关论文
共 50 条
  • [31] PHARMACOKINETICS OF TRANEXAMIC ACID AFTER INTRAVENOUS ADMINISTRATION TO NORMAL VOLUNTEERS
    ERIKSSON, O
    KJELLMAN, H
    PILBRANT, A
    SCHANNONG, M
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1974, 7 (05) : 375 - 380
  • [32] Standard Administration of Tranexamic Acid for Prophylaxis in Endoprosthetics: A good Idea?
    Lier, Heiko
    Kammerer, Tobias
    Knapp, Juergen
    Hofer, Stefan
    Maegele, Marc
    Fries, Dietmar
    von Heymann, Christian
    ORTHOPADE, 2022, 51 (04): : 337 - 338
  • [33] Accidental administration of tranexamic acid into the epidural space: a case report
    Pysyk, Christopher L.
    Filteau, Lucie
    CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2022, 69 (09): : 1169 - 1173
  • [34] CONSIDERATION OF TRANEXAMIC ACID ADMINISTRATION TO COVID-19 PATIENTS
    Ogawa, Haruhiko
    Asakura, Hidesaku
    PHYSIOLOGICAL REVIEWS, 2020, 100 (04) : 1595 - 1596
  • [35] Standard Administration of Tranexamic Acid for Prophylaxis in Endoprosthetics: a good Idea?
    Lier, Heiko
    Kammerer, Tobias
    Knapp, Jurgen
    Hofer, Stefan
    Maegele, Marc
    Fries, Dietmar
    Von Heymann, Christian
    ORTHOPADIE, 2022, 51 (04): : 337 - 338
  • [36] The effect of bolus administration of tranexamic acid in revision hip arthroplasty
    Kazi, Hussain A.
    Fountain, James R.
    Thomas, T. Glyn
    Carroll, Fintan A.
    HIP INTERNATIONAL, 2012, 22 (06) : 615 - 620
  • [37] Topical or intravenous administration of tranexamic acid accelerates wound healing
    Saglam, Sonmez
    Orhan, Zafer
    Arican, Mehmet
    Turhan, Yalcin
    Karaduman, Zekeriya Okan
    Tekce, Yildiray
    Yucel, Muecahid Osman
    JOINT DISEASES AND RELATED SURGERY, 2024, 35 (01): : 85 - 95
  • [38] Timing of tranexamic acid administration in elderly patients with intertrochanteric fracture
    Qiu, Shaodong
    Ma, Tao
    Liu, Haitao
    Wan, Jun
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2020, 13 (10): : 7709 - 7717
  • [39] Tranexamic acid in plastic surgery: routes of administration and dosage considerations
    Khalifa AlGhanim
    Sarah Al-Youha
    Amenah AlWazzan
    Salma AlHamad
    European Journal of Plastic Surgery, 2021, 44 : 295 - 305
  • [40] Efficacy of intravenous tranexamic acid administration in revision hip arthroplasty
    Grzelecki, Dariusz
    Dudek, Piotr
    Okon, Tomasz
    Marczak, Dariusz
    Kordasiewicz, Bartlomiej
    Sibinski, Marcin
    Kowalczewski, Jacek
    ORTHOPADE, 2021, 50 (06): : 464 - 470