Concise Synthesis of Goniothalesdiol A

被引：1
|
作者：
Zeng, Ping Li [1 ]
Zhou, Junhui [2 ]
Yang, Xuechao [1 ]
Wang, Dong [2 ]
Dong, Zhibing [3 ]
机构：
[1] Zhejiang Pharmaceut Coll, Sch Pharmaceut Engn, Ningbo 315100, Zhejiang, Peoples R China
[2] Zhejiang Pharmaceut Coll, Sch Basic Sci, Ningbo 315100, Zhejiang, Peoples R China
[3] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430073, Peoples R China
来源：
LETTERS IN ORGANIC CHEMISTRY | 2022年 / 19卷 / 12期
关键词：
Total synthesis; goniothalesdiol A; styryllactone; L-erythrose; Wacker oxidation; Wittig olefination-Michael addition; DERIVATIVES;
D O I：
10.2174/1570178619666220408121439
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise and efficient synthesis of styryllactone derivative, goniothalesdiol A, has been achieved in the six longest linear steps with 17.7% overall yield. The key steps of our synthesis involved PdCl2-mediated Wacker-type oxidative cyclisation and one-pot tandem Wittig olefination-Michael addition.
引用
收藏
页码：1145 / 1148
页数：4
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