Cocaine-Levamisole Thrombotic Vasculopathy

被引：5
|
作者：
Dy, Irene A. [1 ,2 ]
Wiernik, Peter H. [1 ,2 ]
机构：
[1] St Lukes Roosevelt Hosp, Dept Hematol & Oncol, New York, NY 10019 USA
[2] Continuum Canc Ctr New York, New York, NY USA
来源：
SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2012年 / 38卷 / 08期
关键词：
levamisole; cocaine; agranulocytosis; vasculitis; ANCA; AGRANULOCYTOSIS; ADULTERANT; VASCULITIS;
D O I：
10.1055/s-0032-1328889
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The syndrome of cocaine-levamisole thrombotic vasculopathy is a tetrad of cutaneous manifestations, arthralgia, leukopenia, and positive antineutrophil cytoplasmic antigen (ANCA). Cocaine is cut with levamisole to potentiate its euphoric effects. However, along with this are the adverse reactions of levamisole such as fatal agranulocytosis, flu-like symptoms, and cutaneous thrombotic vasculopathy. High index of suspicion is needed for its diagnosis. This article will review on its toxicities, especially its prothrombotic effects.
引用
收藏
页码：780 / 782
页数：3
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