Copper-catalysedN-arylation of 5-aminopyrazoles: a simple route to pyrazolo[3,4-b]indoles

被引：8
作者：
Chatterjee, Arpita [1 ]
Murmu, Chudamani [1 ]
Peruncheralathan, S. [1 ]
机构：
[1] HBNI, Sch Chem Sci, Natl Inst Sci Educ & Res Bhubaneswar, Khurja 752050, Odisha, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 33期
关键词：
ONE-POT SYNTHESIS; RECENT PROGRESS; DERIVATIVES; INHIBITORS; CYCLIZATION; INDOLES; DESIGN; SAR; IDENTIFICATION; HETEROCYCLES;
D O I：
10.1039/d0ob00812e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A copper-catalysed intramolecularN-arylation of 5-aminopyrazoles is demonstrated for the first time. Highly substituted pyrazolo[3,4-b]indoles are synthesized. In particular, the indole core is decorated with halogens and alkyl and methoxy groups. Furthermore, a selectiveN-arylation of unsymmetrical diaryl bromide containing pyrazoles is exemplified, resulting in valuable pyrazolo[1,5-a]benzimidazoles.
引用
收藏
页码：6571 / 6581
页数：11
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