Homoharringtonine Induces Apoptosis in Human Colorectal Carcinoma HCT116 Cells Via Downregulation of Wnt/β-Catenin Signaling Cascade

被引:5
作者
Park, Mikyung [1 ,2 ]
Kwon, Ho Jeong [2 ]
Kim, Seong Hwan [1 ]
机构
[1] Korea Res Inst Chem Technol, Innovat Target Res Ctr, Bio & Drug Discovery Div, Daejeon 34114, South Korea
[2] Yonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Chem Genom GRL, Seoul 03722, South Korea
关键词
Homoharringtonine; Wnt; beta-Catenin; Porcupine; Colon cancer; CHRONIC MYELOID-LEUKEMIA; BETA-CATENIN; PROTEIN-SYNTHESIS; CANCER CELLS; LUNG-CANCER; CYCLIN D1; INHIBITION; PORCUPINE; ACTIVATION; EXPRESSION;
D O I
10.1002/bkcs.11662
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:196 / 199
页数:4
相关论文
共 50 条
  • [41] [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells
    Ryu, Min Ju
    Chung, Ha Sook
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2015, 51 (01) : 92 - 101
  • [42] Terfenadine, a histamine H1 receptor antagonist, induces apoptosis by suppressing STAT3 signaling in human colorectal cancer HCT116 cells
    Baniya, Manoj Kumar
    Kim, Eun-Hee
    Chun, Kyung-Soo
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [43] Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress
    Salah, Amal
    Bouaziz, Chayma
    Prola, Alexandre
    Da Silva, Julie Pires
    Bacha, Hassen
    Abid-Essefi, Salwa
    Lemaire, Christophe
    JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2017, 80 (23-24): : 1230 - 1241
  • [44] QHMEM, a Quinazolinone Compound, Inhibits Proliferation and Induces Apoptosis in Human Colon Cancer HCT116 Cells
    Long, Ze
    Liao, Xiaolin
    Huang, Jiajun
    Zhang, Na
    Huang, Xiaoming
    Du, Jingjing
    Lin, Wanjun
    Ma, Wenzhe
    LATIN AMERICAN JOURNAL OF PHARMACY, 2019, 38 (04): : 663 - 667
  • [45] Xanthorrhizol, a Natural Sesquiterpenoid, Induces Apoptosis and Growth Arrest in HCT116 Human Colon Cancer Cells
    Kang, You-Jin
    Park, Kwang-Kyun
    Chung, Won-Yoon
    Hwang, Jae-Kwan
    Lee, Sang Kook
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 111 (03) : 276 - 284
  • [46] TNFα induces tolerant production of CXC chemokines in colorectal cancer HCT116 cells via A20 inhibition of ERK signaling
    Zhou, Xin
    An, Dongjian
    Liu, Xueting
    Jiang, Manli
    Yuan, Chuang
    Hu, Jinyue
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 54 : 296 - 302
  • [47] Inonotus obliquus extract induces apoptosis in the human colorectal carcinoma's HCT-116 cell line
    Tsai, Cheng-Chih
    Li, Yu-Sheng
    Lin, Pei-Pei
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 96 : 1119 - 1126
  • [48] Tanshinone IIA induces apoptosis via inhibition of Wnt/β-catenin/MGMT signaling in AtT-20 cells
    Li, Zong-Yang
    Huang, Guo-Dong
    Chen, Lei
    Zhang, Ce
    Chen, Bao-Dong
    Li, Qing-Zhong
    Wang, Xiang
    Zhang, Xie-Jun
    Li, Wei-Ping
    MOLECULAR MEDICINE REPORTS, 2017, 16 (05) : 5908 - 5914
  • [49] Mitochondrial dysfunction suppresses p53 expression via calcium-mediated nuclear factor-kB signaling in HCT116 human colorectal carcinoma cells
    Lee, Young-Kyoung
    Yi, Eui-Yeun
    Park, Shi-Young
    Jang, Won-Jun
    Han, Yu-Seon
    Jegal, Myeong-Eun
    Kim, Yung-Jin
    BMB REPORTS, 2018, 51 (06) : 296 - 301
  • [50] Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells
    Zhao, Lv-Cui
    Li, Jing
    Liao, Ke
    Luo, Nian
    Shi, Qing-Qiang
    Feng, Zi-Qiang
    Chen, Di-Long
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (11): : 27411 - 27421