Homoharringtonine Induces Apoptosis in Human Colorectal Carcinoma HCT116 Cells Via Downregulation of Wnt/β-Catenin Signaling Cascade

被引:5
|
作者
Park, Mikyung [1 ,2 ]
Kwon, Ho Jeong [2 ]
Kim, Seong Hwan [1 ]
机构
[1] Korea Res Inst Chem Technol, Innovat Target Res Ctr, Bio & Drug Discovery Div, Daejeon 34114, South Korea
[2] Yonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Chem Genom GRL, Seoul 03722, South Korea
关键词
Homoharringtonine; Wnt; beta-Catenin; Porcupine; Colon cancer; CHRONIC MYELOID-LEUKEMIA; BETA-CATENIN; PROTEIN-SYNTHESIS; CANCER CELLS; LUNG-CANCER; CYCLIN D1; INHIBITION; PORCUPINE; ACTIVATION; EXPRESSION;
D O I
10.1002/bkcs.11662
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:196 / 199
页数:4
相关论文
共 50 条
  • [21] Chitosan oligosaccharides with degree of polymerization 2-6 induces apoptosis in human colon carcinoma HCT116 cells
    Zou, Pan
    Yuan, Shoujun
    Yang, Xin
    Zhai, Xingchen
    Wang, Jing
    CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 279 : 129 - 135
  • [22] Ginger is an effective inhibitor of HCT116 human colorectal carcinoma in vivo
    Bode, A
    Dong, ZG
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2003, 12 (11) : 1324S - 1324S
  • [23] MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells
    Hwang, Na Lam
    Kang, Yong Jung
    Sung, Bokyung
    Hwang, Seong Yeon
    Jang, Jung Yoon
    Oh, Hye Jin
    Ahn, Yu Ra
    Kim, Do Hyun
    Kim, Su Jeong
    Ullah, Sultan
    Hosain, Mohamad Akbar
    Moon, Hyung Ryong
    Chung, Hae Young
    Kim, Nam Deuk
    ONCOLOGY REPORTS, 2017, 38 (03) : 1783 - 1789
  • [24] MHY2245, a Sirtuin Inhibitor, Induces Cell Cycle Arrest and Apoptosis in HCT116 Human Colorectal Cancer Cells
    Kang, Yong Jung
    Jang, Jung Yoon
    Kwon, Young Hoon
    Lee, Jun Ho
    Lee, Sanggwon
    Park, Yujin
    Jung, Young-Suk
    Im, Eunok
    Moon, Hyung Ryong
    Chung, Hae Young
    Kim, Nam Deuk
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
  • [25] Dioscorea bulbifera induced apoptosis through inhibition of ERK 1/2 and activation of JNK signaling pathways in HCT116 human colorectal carcinoma cells
    Hidayat, Ahmad Fadhlurrahman Ahmad
    Chan, Chim Kei
    Mohamad, Jamaludin
    Kadir, Habsah Abdul
    BIOMEDICINE & PHARMACOTHERAPY, 2018, 104 : 806 - 816
  • [26] Butyrate inhibits the proliferation and induces the apoptosis of colorectal cancer HCT116 cells via the deactivation of mTOR/S6K1 signaling mediated partly by SIRT1 downregulation
    Cao, Mingming
    Zhang, Zhuoran
    Han, Su
    Lu, Xi
    MOLECULAR MEDICINE REPORTS, 2019, 19 (05) : 3941 - 3947
  • [27] Ilimaquinone (Marine Sponge Metabolite) Induces Apoptosis in HCT-116 Human Colorectal Carcinoma Cells via Mitochondrial-Mediated Apoptosis Pathway
    Surti, Malvi
    Patel, Mitesh
    Redhwan, Alya
    Al-Keridis, Lamya Ahmed
    Adnan, Mohd
    Alshammari, Nawaf
    Reddy, Mandadi Narsimha
    MARINE DRUGS, 2022, 20 (09)
  • [28] Terfenadine, a histamine H1 receptor antagonist, induces apoptosis by suppressing STAT3 signaling in human colorectal cancer HCT116 cells
    Baniya, Manoj Kumar
    Kim, Eun-Hee
    Chun, Kyung-Soo
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [29] Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress
    Salah, Amal
    Bouaziz, Chayma
    Prola, Alexandre
    Da Silva, Julie Pires
    Bacha, Hassen
    Abid-Essefi, Salwa
    Lemaire, Christophe
    JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2017, 80 (23-24): : 1230 - 1241
  • [30] QHMEM, a Quinazolinone Compound, Inhibits Proliferation and Induces Apoptosis in Human Colon Cancer HCT116 Cells
    Long, Ze
    Liao, Xiaolin
    Huang, Jiajun
    Zhang, Na
    Huang, Xiaoming
    Du, Jingjing
    Lin, Wanjun
    Ma, Wenzhe
    LATIN AMERICAN JOURNAL OF PHARMACY, 2019, 38 (04): : 663 - 667