Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children

被引:93
作者
Abu-Diab, Afaf [1 ]
Azzeh, Maysa [2 ]
Ghneim, Raed [1 ]
Ghneim, Riyad [1 ]
Zoughbi, Madeleine [1 ]
Turkuman, Sultan [1 ]
Rishmawi, Nabeel [1 ]
Issa, Abed-El-Razeq [1 ]
Siriani, Issa [1 ]
Dauodi, Rula [1 ]
Kattan, Randa [1 ]
Hindiyeh, Musa Y. [1 ]
机构
[1] Caritas Baby Hosp, Clin Lab Div, Bethlehem, Palestine
[2] Al Quds Univ, Jerusalem, Israel
关键词
D O I
10.1128/JCM.00369-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this prospective study we compared the use of pernasal flocked swab samples with the use of nasopharyngeal aspirate (NPA) samples for the detection of respiratory viruses from 455 children less than 5 years of age. Overall, the sensitivity and the specificity of the pernasal flocked swab samples were 98.5% and 100%, respectively. The excellent sensitivity of the flocked swab samples in combination with the rapid means by which they may be collected makes them an alternative to NPA samples, whose collection is more invasive.
引用
收藏
页码:2414 / 2417
页数:4
相关论文
共 16 条
[1]   COMPARISON OF NASOPHARYNGEAL ASPIRATE AND NASOPHARYNGEAL SWAB SPECIMENS FOR RESPIRATORY SYNCYTIAL VIRUS DIAGNOSIS BY CELL-CULTURE, INDIRECT IMMUNOFLUORESCENCE ASSAY, AND ENZYME-LINKED-IMMUNOSORBENT-ASSAY [J].
AHLUWALIA, G ;
EMBREE, J ;
MCNICOL, P ;
LAW, B ;
HAMMOND, GW .
JOURNAL OF CLINICAL MICROBIOLOGY, 1987, 25 (05) :763-767
[2]   COMPARISON OF NASAL BRUSH AND NASOPHARYNGEAL ASPIRATE TECHNIQUES IN OBTAINING SPECIMENS FOR DETECTION OF RESPIRATORY SYNCYTIAL VIRAL-ANTIGEN BY IMMUNOFLUORESCENCE [J].
BARNES, SD ;
LECLAIR, JM ;
FORMAN, MS ;
TOWNSEND, TR ;
LAUGHLIN, GM ;
CHARACHE, P .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1989, 8 (09) :598-601
[3]   Comparison of nasopharyngeal flocked swabs and aspirates for rapid diagnosis of respiratory viruses in children [J].
Chan, K. H. ;
Peiris, J. S. M. ;
Lim, W. ;
Nicholls, J. M. ;
Chiu, S. S. .
JOURNAL OF CLINICAL VIROLOGY, 2008, 42 (01) :65-69
[4]   ISOLATION OF VIRUSES FROM NASOPHARYNGEAL SECRETIONS - COMPARISON OF ASPIRATION AND SWABBING AS MEANS OF SAMPLE COLLECTION [J].
CRUZ, JR ;
QUINONEZ, E ;
DEFERNANDEZ, A ;
PERALTA, F .
JOURNAL OF INFECTIOUS DISEASES, 1987, 156 (02) :415-416
[5]   Comparison of flocked and rayon swabs for collection of respiratory epithelial cells from uninfected volunteers and symptomatic patients [J].
Daley, Peter ;
Castriciano, Santina ;
Chernesky, Max ;
Smieja, Marek .
JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (06) :2265-2267
[6]   NASOPHARYNGEAL SWABS AND NASOPHARYNGEAL ASPIRATES EQUALLY EFFECTIVE FOR THE DIAGNOSIS OF VIRAL RESPIRATORY-DISEASE IN HOSPITALIZED CHILDREN [J].
FRAYHA, H ;
CASTRICIANO, S ;
MAHONY, J ;
CHERNESKY, M .
JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (06) :1387-1389
[7]   CLINICALLY USEFUL METHOD FOR ISOLATION OF RESPIRATORY SYNCYTIAL VIRUS [J].
HALL, CB ;
DOUGLAS, RG .
JOURNAL OF INFECTIOUS DISEASES, 1975, 131 (01) :1-5
[8]   Antivirals for influenza: Historical perspectives and lessons learned [J].
Hayden, Frederick G. .
ANTIVIRAL RESEARCH, 2006, 71 (2-3) :372-378
[9]   Nasal swab versus nasopharyngeal aspirate for isolation of respiratory viruses [J].
Heikkinen, T ;
Marttila, J ;
Salmi, AA ;
Ruuskanen, O .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) :4337-4339
[10]   Diagnostic assays for respiratory syncytial virus disease [J].
Henrickson, Kelly J. ;
Hall, Caroline Breese .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2007, 26 (11) :S36-S40