Four C-geranyl flavonoids from the flowers of Paulownia fortunei and their anti-inflammatory activity

被引：10

作者：

Zhang, Jing-Ke ^{[1
,2
]}

Li, Meng ^{[1
,2
]}

Li, Miao ^{[1
,2
]}

Du, Kun ^{[1
,2
]}

Lv, Jinjin ^{[1
,2
]}

Zhang, Zhi-Guang ^{[1
,2
]}

Zheng, Xiao-Ke ^{[1
,2
]}

Feng, Wei-Sheng ^{[1
,2
]}

机构：

[1] Henan Univ Chinese Med, Zhengzhou, Peoples R China

[2] Collaborat Innovat Ctr Resp Dis Diag & Treatment, Zhengzhou, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 22期

关键词：

Paulownia fortunei; C-geranyl flavonoids; anti-inflammatory activity; CATALPIFOLIA GONG TONG; TOMENTOSA FRUITS; INHIBITION; FLAVANONES; CELLS; DIFFERENTIATION; PROLIFERATION;

D O I：

10.1080/14786419.2018.1556263

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Four new C-geranyl flavonoids, paulownione D-G (1-4) were isolated from the 50% acetone-H2O extract of the flowers of Paulownia fortunei. The structures of the compounds were determined by extensive spectroscopic analyses (UV, IR, HR-ESI-MS, 1D and 2D NMR). All of the compounds (1-4) exhibited potent protection effects in H9c2 cardiocytes against the lipopolysaccharide (LPS)-induced inflammation.

引用

页码：3189 / 3198

页数：10

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