Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase

被引：94
作者：
Fowler, Jason D. [1 ]
Suo, Zucai [1 ]
机构：
[1] Ohio State Univ, Dept Biochem, Columbus, OH 43210 USA
来源：
CHEMICAL REVIEWS | 2006年 / 106卷 / 06期
关键词：
D O I：
10.1021/cr040445w
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This review explores the world of deoxyribonucleic (DNA) polymerases and attempts to define TdT in relation to its peers. Focus is on the enzymatic functions, physical characteristics, and regulation of TdT. The process of V(D)J recombination is also explored and some preliminary work suggesting that TdT may play a role in specific types of learning and memory storage discussed.
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收藏
页码：2092 / 2110
页数：19
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